Ross Lake

Ross Lake
Facility Head
Head, Microscopy Core Facility

Ross Lake is the head of the Laboratory of Genitourinary Cancer Pathogenesis (LCGP) Microscopy Core Facility, which provides state-of-the-art equipment, materials, and expertise to researchers in the LGCP. In addition, the Core is open to scientists at the National Cancer Institute. The Core instruments include a Carl Zeiss LSM 780 laser scanning confocal microscope, a Zeiss AxioScan Z1 fluorescent slide scanner, an Olympus VivaView Incubator Microscope, and a pair of Carl Zeiss Axio Observer epifluorescent microscopes. The Core provides access to cutting-edge technology and training on the Core's instruments as well as assistance with experimental design.

Areas of Expertise
1) microscopy, 2) immunofluorescence, 3) immunohistochemistry

Contact Info

Ross Lake
Center for Cancer Research
National Cancer Institute
Building 37, Room 1066
Bethesda, MD 20892
Ph: 240-760-6824
laker@mail.nih.gov

In addition to managing the LGCP Microscopy Core, Ross also conducts research in collaboration with Dr. Kathy Kelly on the role of CD97, an adhesion class GPCR, in tumor progression and metastasis.

Scientific Focus Areas:
Cancer Biology, Cell Biology

Selected Recent Publications

  1. Ward Y, Lake R, Faraji F, Sperger J, Martin P, Gilliard C, Ku KP, Rodems T, Niles D, Tillman H, Yin J, Hunter K, Sowalsky AG, Lang J, Kelly K.
    Cell Reports. 23(3): 808-822, 2018. [ Journal Article ]
  2. Staunton JR, Vieira W, Fung KL, Lake R, Devine A, Tanner K.
    Cell Mol Bioeng. 9(3): 398-417, 2016. [ Journal Article ]
  3. Zhang L, Boufraqech M, Lake R, Kebebew E.
    Oncotarget. 7(13): 16517-28, 2016. [ Journal Article ]
  4. Agarwal S, Hynes PG, Tillman HS, Lake R, Abou-Kheir WG, Fang L, Casey OM, Ameri AH, Martin PL, Yin JJ, Iaquinta PJ, Karthaus WR, Clevers HC, Sawyers CL, Kelly K.
    Cell Reports. 13: 2147–2158, 2015. [ Journal Article ]
  5. Ward Y, Lake R, Martin PL, Killian K, Salerno P, Wang T, Meltzer P, Merino M, Cheng SY, Santoro M, Garcia-Rostan G, Kelly K.
    Oncogene. 32: 2726-2738, 2013. [ Journal Article ]

Ross Lake has been a SRA in the LGCP Microscopy Core Facility in the Center for Cancer Research of the NCI for over 14 years.  He has extensive experience in cell and molecular biology, immunohistochemistry, immunofluorescence, as well as in microscopy.  Ross has managed the LGCP Microscopy Core Facility since December 2014.

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