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Christina H. Stuelten, M.D., Ph.D.

Christina H. Stuelten, M.D., Ph.D.

  • Center for Cancer Research
  • National Cancer Institute

RESEARCH SUMMARY

Dr. Stuelten’s research focuses on TGF-beta signaling and its role in cell migration, tissue repair and tumor disease. Her work has led to the identification of mechanisms that underlie tumor progression and wound-promoted tumor growth.

Areas of Expertise

Mechanisms Of TGF-beta - Induced Alternative Splicing
Effect of Smurf2 Loss on Wound Healing of the Skin
Effect of Stromal Smurf2 Loss on Tumor Progression

Publications

Selected Publications

Smurf2 Regulates Inflammation and Collagen Processing in Cutaneous Wound Healing through Transforming Growth Factor-β/Smad3 Signaling

Stuelten CH, Melis N, Subramanian B, Tang Y, Kimicata M, Fisher JP, Weigert R, Zhang YE.
American Journal of Pathology. 192: 1699 - 1711, 2022.
Full-Text Article
[ Journal Article ]

Transforming Growth Factor-β: An Agent of Change in the Tumor Microenvironment.

Stuelten CH, Zhang YE
Front Cell Dev Biol.. 9: 764727, 2021. [ Journal Article ]

TGF-β-induced alternative splicing of TAK1 promotes EMT and drug resistance.

Tripathi V, Shin JH, Stuelten CH, Zhang YE
Oncogene. 38(17): 3185-3200, 2019. [ Journal Article ]

Cell motility in cancer invasion and metastasis: insights from simple model organisms.

Stuelten CH, Parent CA, Montell DJ
Nat Rev Cancer. 18(5): 296-312, 2018. [ Journal Article ]

SDF-1a mediates wound-promoted tumor growth in a syngeneic orthotopic mouse model of breast cancer

Stuelten CH, Cervoni-Curet FN, Busch JI, Sutton E, Webster JD, Kavalukas SL, Wakefield LM, Barbul A, Niederhuber JE.
PLoS ONE. Apr 11;8(4): e60919, 2013. [ Journal Article ]