Our Publications
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HIV Dynamics and Replication Program
HIV Dynamics and Replication Program
HIV Dynamics and Replication Program
HIV Dynamics and Replication Program
HIV Dynamics and Replication Program
HIV Dynamics and Replication Program
HIV Dynamics and Replication Program
HIV Dynamics and Replication Program
HIV Dynamics and Replication Program
Our Publications
Preprints and Accepted Manuscripts
- HIV-1 integrase inhibitors with modifications that affect their potencies against drug resistant integrase mutants
- ACS Infect. Dis., in press Feb 18, 2021
- Mechanism of viral glycoprotein targeting by membrane-associated-RING-CH proteins
- mBio, in press Jan 28, 2021, doi: 10.1101/2021.01.25.428025.
- CryoET structures of immature HIV Gag reveal a complete six-helix bundle and stabilizing small molecules distinct from IP6
- bioRxiv Oct 31, 2020, doi: 10.1101/2020.10.31.363382.
- SERINC proteins potentiate antiviral type I IFN induction and proinflammatory signaling pathways
- Sci Signal, in press Oct 19, 2020.
- Early emergence and long-term persistence of HIV-infected T cell clones in children
- bioRxiv Sept 15, 2020, doi: 10.1101/2020.09.15.298406.
Recent Publications
- Integrase strand transfer inhibitors are effective anti-HIV drugs
- Viruses 13:205, 2021.
- Development of a cell-based luciferase complementation assay for identification of SARS-CoV-2 3CLpro inhibitors
- Viruses 13:173, 2021.
- Efficient HIV-1 in vitro reverse transcription: optimal capsid stability is required
- Signal Transduct Target Ther 6:13, 2021.
- Mechanistic analysis of the broad antiretroviral resistance conferred by HIV-1 envelope glycoprotein mutations
- mBio 12: e03134-20, 2021.
- Oncogenic HPV promotes the expression of the long noncoding RNA lnc-FANCI-2 through E7 and YY1
- Proc Natl Acad Sci U S A 118: e2014195118, 2021.
- Structure-based non-nucleoside inhibitor design: Developing inhibitors that are effective against resistant mutants
- Chem Biol Drug Des 97: 4-17, 2021.
- Specific guanosines in the HIV-2 leader RNA are essential for efficient viral genome packaging
- J Mol Biol 433: 166718, 2021.
- PSGL-1 Inhibits the incorporation of SARS-CoV and SARS-CoV-2 spike glycoproteins into pseudovirions and impairs pseudovirus attachment and infectivity
- Viruses 13: E46, 2020.
- Opposing activities of IFITM proteins in SARS-CoV-2 infection
- EMBO J e106501, 2020.
- Structural mimicry drives HIV-1 Rev-mediated HERV-K expression
- J Mol Biol 432: 166711, 2020.
- How to package the RNA of HIV-1
- eLife 9: e63585, 2020.
- Impact of nuclear export pathway on cytoplasmic HIV-1 RNA transport mechanism and distribution
- mBio 11: e01578-20, 2020.
- Elucidating the basis for permissivity of the MT-4 T-cell line to replication of an HIV-1 mutant lacking the gp41 cytoplasmic tail
- J Virol 94: e01334-20, 2020.
- HIV-DRLink: A tool for reporting linked HIV-1 drug resistance mutations in large single-genome datasets using the Stanford HIV Database
- AIDS Res Hum Retroviruses 36: 942-947, 2020.
- HIV-1 viremia not suppressible by antiretroviral therapy can originate from large T-cell clones producing infectious virus
- J Clin Invest 130: 5847-5857, 2020.
- Homology-guided identification of a conserved motif linking the antiviral functions of IFITM3 to its oligomeric state
- eLife 9: e58537, 2020.
- Crystal structure of a soluble APOBEC3G variant suggests ssDNA to bind in a channel that extends between the two domains
- J Mol Biol 432: 6042-6060, 2020.
- HIV-1 Gag protein with or without p6 specifically dimerizes on the viral RNA packaging signal
- J Biol Chem 295: 14391-14401, 2020.
- Unpaired guanosines in the 5' untranslated region of HIV-1 RNA act synergistically to mediate genome packaging
- J Virol 94: e00439-20, 2020.
- Low genetic diversity may be an Achilles heel of SARS-CoV-2
- Proc Natl Acad Sci U S A 117: 24614-24616, 2020.
- HIV-1 maturation: Lessons learned from inhibitors
- Viruses 12: 940, 2020.
- HIV-1 integrase inhibitors that are active against drug-resistant integrase mutants
- Antimicrob Agents Chemother 64: e00611-29, 2020.
- The heart of the HIV RNA packaging signal?
- Proc Natl Acad Sci U S A 117: 19621-19623, 2020.
- Use of drug-level testing and single-genome sequencing to unravel a case of HIV seroconversion on PrEP
- Clin Infect Dis, in press July 20, 2020.
- Effect of P-body component Mov10 on HCV virus production and infectivity
- FASEB J 34: 9433-9449, 2020.