Scot Niglio, M.D., M.S.

Scot Niglio, M.D., M.S.
Assistant Research Physician

Team Member of:

Dr. Niglio is a medical oncologist who specializes in the care of patients with genitourinary cancers (prostate, kidney, bladder, testicular). His research focuses on using a person’s own immune system to fight cancer. He also develops treatments personalized to an individual patient’s cancer based on gene mutations and tumor characteristics.

Dr. Niglio is board certified in internal medicine and medical oncology.

Areas of Expertise

1) genitourinary cancers, 2) bladder cancer, 3) rare genitourinary cancers, 4) immuno-oncology, 5) immunotherapy, 6) personalized medicine

Contact Info

Scot Niglio, M.D., M.S.
Center for Cancer Research
National Cancer Institute
Building 10, Room 12C342B
Bethesda, MD 20892
Ph: 240-858-7055

Dr. Niglio develops new treatments for genitourinary cancers (bladder, prostate, kidney, and testicular cancers). His research focuses on using a person’s own immune system to fight cancer. He also develops treatments personalized to an individual patient’s cancer based on gene mutations and tumor characteristics.

NIH Scientific Focus Areas:
Cancer Biology, Clinical Research, Genetics and Genomics, Immunology
View Dr. Niglio's PubMed Summary

Selected Key Publications

  1. Niglio SA, Jia R, Ji J, Ruder S, Patel VG, Martini A, Sfakianos JP, Marqueen KE, Waingankar N, Mehrazin R, Wiklund P, Oh WK, Mazumdar M, Ferket BS, Galsky MD.
    European Urology. Epub ahead of print, 2019. [ Journal Article ]
  2. Marqueen KE, Waingankar N, Sfakianos JP, Mehrazin R, Niglio SA, Audenet F, Jia R, Mazumdar M, Ferket BS, Galsky MD.
    JNCI Cancer Spectrum. 2(4): pky075, 2018. [ Journal Article ]
  3. DNA Damage Response as Biomarkers Informing a Precision Medicine Approach to Bladder Cancer: What are the Next Steps?.
    Expert Review of Precision Medicine and Drug Development. 4: 7-9, 2019.
  4. Audenet F, Waingankar N, Ferket BS, Niglio SA, Marqueen KE, Sfakianos JP, Galsky MD.
    The Journal of Urology. 200(5): 996-1004, 2018. [ Journal Article ]
  5. Laganà A, Beno I, Melnekoff D, Leshchenko V, Madduri D, Ramdas D, Sanchez L, Niglio S, Perumal D, Kidd BA, Miotto R, Shaknovich R, Chari A, Cho HJ, Barlogie B, Jagannath S, Dudley JT, Parekh S.
    JCO Precision Oncology. Epub 2018 Aug 8, 2018. [ Journal Article ]

Dr. Scot Niglio graduated from Villanova University with a Bachelor of Science in biology where he was inducted into the Phi Beta Kappa Honor Society and went on to receive a Master of Science in physiology from Georgetown University. He then earned a Master of Science in clinical and translational science at Rutgers University in combination with his medical degree. He completed his internal medicine residency as well as a hematology and medical oncology fellowship at the Icahn School of Medicine at Mount Sinai. Dr. Niglio has received honors such as the Young Investigator Award (2019) from the Conquer Cancer Foundation (ASCO) and he has been named "40 under 40 in Cancer" (2019) by the Lynx Group. This award recognizes the contributions being made by rising stars and emerging leaders across the field of cancer research under the age of 40.