Charalampos “Harris” S. Floudas, MD, DMSc, MS
- Center for Cancer Research
- National Cancer Institute
- Building 10, Room 13N240
- Bethesda, MD, 20892
- 240-858-3032
- charalampos.floudas@nih.gov
RESEARCH SUMMARY
Dr. Floudas is a Head and Neck Cancer (HNC) Medical Oncologist. He is clinically active in drug development for HNC, designing and conducting early-phase immunotherapy clinical trials, addressing Squamous Cell Cancer of the Head and Neck (HNSCC/SCCHN), but also rare cancers, such as Nasopharyngeal Cancer and Olfactory Neuroblastoma (esthesioneuroblastoma). His translational research interests include applying artificial intelligence (AI) and machine learning (ML) to multi-modal omics data for clinical predictive modeling and biomarker discovery, and the exploration of LLM applications in Oncology, particularly in patient-clinical trial matching. He is also studying cancer disparities, focusing in equitable access to cancer clinical trials.
Areas of Expertise
Information for Patients
Learn more about our clinical trials and the highly specialized care teams that lead them.
Charalampos “Harris” S. Floudas, MD, DMSc, MS
Clinical Trials
Research
Dr Floudas’ research focuses in head and neck cancer and tumor immunology. He is working closely with the scientists of the Center for Immuno-Oncology and the Otolaryngology Surgeon-Scientists of the NCI Surgical Oncology Program, and is studying novel combinations of immunotherapeutic agents aiming to improve the efficacy of immunotherapy in head and neck cancers.
Publications
A Pilot Study of the PD-1 Targeting Agent AMP-224 Used With Low-Dose Cyclophosphamide and Stereotactic Body Radiation Therapy in Patients With Metastatic Colorectal Cancer
Biography
Charalampos “Harris” S. Floudas, MD, DMSc, MS
Dr. Floudas received his medical degree from the University of Crete, Greece, (MD, 2000), and completed an Internal Medicine residency at the University of Athens, Greece (2008), from which he received a research doctorate in medicine (DMSc, 2009) while serving as an Oncology Research Associate.
Subsequently, he studied Biomedical Informatics in the University of Pittsburgh (MS, 2012), and was a visiting research scholar in the Center for Health and Biomedical Informatics of the New York University (2013).
Following Internal Medicine residency (Maimonides Medical Center, Brooklyn, NY, 2016), he graduated from the NIH Hematology Oncology Fellowship (2019) and joined the NCI Genitourinary Malignancies Branch to develop a Head and Neck Cancer program, moving to the Center for Immuno-Oncology in May 2022.
