Julio C. Valencia, M.D.
Dr Valencia's main interest is the analysis of trafficking and sorting mechanisms of melanocyte-specific proteins, both in melanocytes and in melanoma cells. His primary expertise is the analysis and applications of confocal microscopy with emphasis on the subcellular localization for organelle proteins.
1) confocal microscopy
- Pigment Cell Melanoma Res. 27: 82-9, 2014. [ Journal Article ]
- J Invest Dermatol. 132: 2791-9, 2012. [ Journal Article ]
Sialylated core 1 O-glycans influence the sorting of Pmel17/gp100 and determine its capacity to form fibrils.J Biol Chem. 282: 11266-80, 2007. [ Journal Article ]
Intracellular composition of fatty acid affects the processing and function of tyrosinase through the ubiquitin-proteasome pathway.Biochem J. 394: 43-50, 2006. [ Journal Article ]
Melanosomal sequestration of cytotoxic drugs contributes to the intractability of malignant melanomas.Proc Natl Acad Sci U S A. 103: 9903-7, 2006. [ Journal Article ]
Julio C. Valencia, M.D. is a staff scientist in the Laboratory of Experimental Immunology, Cancer and Inflammation Program. In 1997, he received both his bachelor in medicine degree and medical doctor degree from San Marcos University School of Medicine in Lima, Peru. Following an internship and internal medicine training at Edgardo Rebagliatti Martins Hospital, Lima, Peru, he completed a 3-year postdoctoral fellowship in the Pathology Section and Pulmonary Critical Care Medicine Branch at the National, Heart, Lung, and Blood Institute (NHLBI). HIs primary expertise is the analysis and application of confocal microscopy with an emphasis on the subcellular localization of organelle proteins. Dr. Valencia is author and co-author of several scientific papers on basic research published in highly respected scientific journals such as Proceedings of the National Academy of Sciences U S A, Journal of Cell Science, FASEB Journal, and Biochemical Journal. Dr Valencia's main interest is the analysis of trafficking and sorting mechanisms of melanocyte-specific proteins both in melanocytes and in melanoma cells.