Model
Descriptor |
Gene Name |
Investigator's Last Name |
Mutation
Type |
Strain
Background |
 |
| Fgf8flox |
Fgf8 |
Lewandoski |
Targeted Mutation |
Mixed Genetic Background |
| Fgf8neo |
Fgf8 |
Lewandoski |
Targeted Mutation |
Mixed Genetic Background |
| Fgf8 delta 2,3 |
Fgf8 |
Lewandoski |
Null |
Mixed Genetic Background |
| Gbx2flox |
Gbx2 |
Lewandoski |
Targeted Mutation |
Mixed Genetic Background |
| Gbx2deltahb |
Gbx2 |
Lewandoski |
Null |
Mixed Genetic Background |
| Alk3 null |
Bmpr1a |
Lewandoski |
Null |
Mixed Genetic Background |
| Alk3 floxed |
Bmpr1a |
Lewandoski |
Targeted Mutation |
Other |
| Z/AP/ |
Alkaline Phosphatase reporter |
Lewandoski |
Transgenic |
FVB/N |
| ROSA26 Reporter |
Gtrosa26 tm1Sor |
Lewandoski |
Knock-in |
C57BL/6 |
| beta actin-Cre |
Cre |
Lewandoski |
cre Transgenic |
Mixed Genetic Background |
| Zp3-Cre |
Cre |
Lewandoski |
cre Transgenic |
FVB/N |
| Msx2-Cre |
Cre |
Lewandoski |
cre Transgenic |
Mixed Genetic Background |
| T-Cre |
Cre |
Lewandoski |
cre Transgenic |
C57BL/6 |
| Evx1-Cre |
Cre |
Lewandoski |
cre Transgenic |
C57BL/6 |
| En1-Cre |
Cre |
Lewandoski |
cre Transgenic |
C57BL/6 |
| Ap2-Cre |
Cre |
Lewandoski |
cre Transgenic |
Unknown |
| MIN |
Apc |
Schlom |
Targeted Mutation |
C57BL/6 |
| B-gal Tg |
beta-galactosidase |
Schlom |
Transgenic |
Other |
| Zap70 knock out |
Zap70
Zap70 zeta-chain (TCR) associated protein kinase |
Bosselut |
Targeted Mutation |
Mixed Genetic Background |
| ADA Zap70 transgenic |
Zap70, zeta-chain (TCR) associated protein kinaseZap70 zeta-chain (TCR) associated protein kinase |
Bosselut |
Multiple Mutations |
Mixed Genetic Background |
| Zap70 CD5 double knock out |
Zap70, CD5 |
Bosselut |
Targeted Mutation |
Mixed Genetic Background |
| Zap70 knock out, Bcl-2 transgenic |
Zap70, B-cell leukemia/lymphoma 2 |
Bosselut |
Multiple Mutations |
Unknown |
| Zap70 knock-out, AND TCR transgenic |
Zap70, T-cell Receptor |
Bosselut |
Multiple Mutations |
Unknown |
| Zap70, HY TCR transgenic |
Zap70, T-cell Receptor |
Bosselut |
Multiple Mutations |
Unknown |
| Zap70 knok-out, P14 TCR transgenic |
Zap70, T-cell Receptor |
Bosselut |
Multiple Mutations |
Mixed Genetic Background |
| beta actin promoter linked to tv-a receptor |
tv-a |
Hughes |
Transgenic |
Mixed Genetic Background |
| tap knockout |
tap |
Hughes |
Targeted Mutation |
C57BL/6 |
| Brca2 knockout |
Brca2 |
Sharan |
Targeted Mutation |
Mixed Genetic Background |
| BRCA1 humanized mice |
Brca1 |
Sharan |
Transgenic |
Mixed Genetic Background |
| Brca1-1700T knockout |
Brca1 |
Sharan |
Targeted Mutation |
Mixed Genetic Background |
| trkA knockout |
Ntrk1 |
Tessarollo |
|
Mixed Genetic Background |
| trkC knockout |
Ntrk3 |
Tessarollo |
Null |
C57BL/6 |
| BDNF knockout |
Brain Derived Neurotrophic Factor |
Tessarollo |
Null |
C57BL/6 |
| NT-5 knockout |
Nerotrophin 5 |
Tessarollo |
Null |
C57BL/6 |
| NT-3 knockout |
Neurotrophin-3 |
Tessarollo |
Null |
C57BL/6 |
| p75 knockout |
Nerve Growth Fcator Receptor |
Tessarollo |
Null |
C57BL/6 |
| NGF knockout |
Nerve Growth Factor |
Tessarollo |
Null |
C57BL/6 |
| TrkC kinase knockout |
Ntrk3 |
Tessarollo |
Targeted Mutation |
C57BL/6 |
| BDNF knocked in the NT-3 locus |
Not applicable |
Tessarollo |
Knock-in |
Mixed Genetic Background |
| Mus musculus musculus (CzechII) |
|
Callahan |
None |
Other |
| Mus spretus (Spret) |
|
Callahan |
None |
Other |
| Balb/cfCzechII |
|
Callahan |
None |
BALB/c |
| Balb/cfSpret |
|
Callahan |
None |
BALB/c |
| Balb/cP53f CzechII |
p53 |
Callahan |
Null |
BALB/c |
| CzechII X WAP-Int3 |
|
Callahan |
Transgenic |
Other |
| MMTV-revTet/Tetop-GFP |
|
Callahan |
Transgenic |
FVB/N |
| CzechII-Int3+/- |
|
Callahan |
Null |
Other |
| FVB-Int3 +/- |
|
Callahan |
Null |
FVB/N |
| WAP-numb |
Numb |
Callahan |
Transgenic |
FVB/N |
| MMTV LTR-Int3 |
Notch4 |
Callahan |
Transgenic |
FVB/N |
| WAP-Int3 |
Notch4 |
Callahan |
Transgenic |
FVB/N |
| WAP3-Int3sh |
Notch4 |
Callahan |
Transgenic |
FVB/N |
| Int3 -/- |
Notch4 |
Callahan |
Null |
Mixed Genetic Background |
| C/EBPbeta knockout |
Cebpb |
Sterneck |
Null |
129 |
| C/EBPbeta knockout |
Cebpb |
Sterneck |
Null |
C57BL/6 |
| C/EBPdelta knockout |
Cebpd |
Sterneck |
Null |
129 |
| C/EBPdelta knockout |
Cebpd |
Sterneck |
Null |
C57BL/6 |
| C/EBPbeta floxed |
Cebpb |
Sterneck |
Targeted Mutation |
C57BL/6 |
| Selenocysteine tRNA (TRSP) -i6A transgenic |
TRSP |
Kraemer |
Targeted Mutation |
FVB/N |
| Selenocysteine tRNA (TRSP) WT transgenic |
TRSP |
Kraemer |
None |
FVB/N |
| Ulip ko |
Dihydropyrimidinase-like 3 |
Thiele-Galetto |
Knock-in |
129 |
| MMTV-CR-1 |
TDGF-1 |
Salomon |
Transgenic |
FVB/N |
| WAP-CR-1 |
TDGF-1 |
Salomon |
Transgenic |
FVB/N |
| WAP-Cre |
Mm Wap-Cre |
Smith |
cre Transgenic |
Mixed Genetic Background |
| p53 |
p53 |
Smith |
Null |
BALB/c |
| Rosa26-lox-stop-lox-LacZ |
|
Smith |
Knock-in |
Mixed Genetic Background |
| WAP-TGFb1 |
TGFbeta1 |
Smith |
Transgenic |
FVB/N |
| WAP-Cre |
|
Smith |
Transgenic |
Mixed Genetic Background |
| Telomerase knockout |
Terc |
Smith |
Null |
Mixed Genetic Background |
| WAP-Int6sh |
Mm Eif3s6 |
Smith |
Transgenic |
FVB/N |
| MMTV-Msx-1 |
#17701 homeo box, msh-like 1 |
Vonderhaar |
Transgenic |
FVB/N |
| il-7receptor knockout |
|
Durum |
Targeted Mutation |
C57BL/6 |
| il-7 knockout |
|
Durum |
Targeted Mutation |
Mixed Genetic Background |
| Bax -/- |
Bax |
Durum |
Null |
C57BL/6 |
| IL-7R alpha |
Il7r |
Durum |
Null |
C57BL/6 |
| Rag2 -/- |
Rag2 |
Durum |
Null |
C57BL/6 |
| Id1 knockout |
Id1 |
Keller |
Null |
C57BL/6 |
| Jak3 Knockout |
Janus Kinase 3 |
Keller |
Null |
C57BL/6 |
| Sfrp1 knockout |
Sfrp1 |
Rubin |
Other |
Mixed Genetic Background |
| LAP-tTA |
tetracycline transactivator |
Zhang |
Transgenic |
FVB/N |
| MMTV-tTA |
tetracycline transactivator |
Zhang |
Transgenic |
FVB/N |
| soluble HEL Transgenic |
ML5sHEL |
Schiller |
Transgenic |
C57BL/6 |
| HEL specific Ig |
IghelMD4 |
Schiller |
Transgenic |
C57BL/6 |
| SCL/LMO1 transgenic |
TAL1, LMO1 |
Aplan |
Transgenic |
C57BL/6 |
| NUP98-HOXD13 transgenic |
NUP98-HOXD13 fusion |
Aplan |
Transgenic |
C57BL/6 |
| cdd |
perforin and Tnfsf6 |
Sayers |
|
BALB/c |
| perforin knockout |
perforin |
Sayers |
Null |
C57BL/6 |
| perforin knockout |
perforin |
Sayers |
Null |
BALB/c |
| gld |
tnfsf6 |
Sayers |
|
C57BL/6 |
| lpr |
tnfrsf6 |
Sayers |
|
BALB/c |
| Ifng transgenic |
Interferon-gamma (mouse) |
Young |
Transgenic |
C57BL/6 |
| Wip1 (Ppm1d) |
protein phosphatase 1D magnesium-dependent, delta isoform |
Appella |
Null |
Mixed Genetic Background |
| Pigment mutant |
Slaty |
Hearing |
Congenic |
C57BL/6 |
| Pigment mutant |
Agouti - lethal yellow mutation |
Hearing |
Congenic |
C57BL/6 |
| Pigment mutant |
nonagouti |
Hearing |
Congenic |
C57BL/6 |
| Pigment mutant |
albino |
Hearing |
Congenic |
BALB/c |
| Pigment mutant |
Agouti |
Hearing |
Other |
Other |
| Mouse Model of Human Beta-Sickle Cell Disease |
sickle, skl |
Keefer |
Other |
Mixed Genetic Background |
| IL-15 transgenic |
IL15 |
Waldmann |
Transgenic |
C57BL/6 |
| IL-15Ra transgenic |
HS IL15RA |
Waldmann |
Transgenic |
C57BL/6 |
| A2Kb |
HLA-A*0201/H-2Kb chimera |
Berzofsky |
Transgenic |
C57BL/6 |
| BALB.A10 |
H-2a |
Berzofsky |
Congenic |
BALB/c |
| BALB.B |
H-2b |
Berzofsky |
Congenic |
BALB/c |
| BALB.K |
H-2k |
Berzofsky |
Congenic |
BALB/c |
| AAD |
HLA-A*0201/H-2Dd |
Berzofsky |
Transgenic |
C57BL/6 |
| BALB/c-Neu |
Her-2/neu |
Berzofsky |
Transgenic |
BALB/c |
| BALB-CD1 KO |
CD1d |
Berzofsky |
Targeted Mutation |
BALB/c |
| HHD-2 |
HLA-A*0201/H-2Db |
Berzofsky |
Multiple Mutations |
C57BL/6 |
| B7Kb |
HLA-B7/H-2Kb chimera |
Berzofsky |
Transgenic |
C57BL/6 |
| BALB/c-C1Nuc |
NFATc mutant |
Berzofsky |
Transgenic |
BALB/c |
| HER-2/neu transgenic (BALB/c-neuT) |
HER-2/neu/ErbB2 |
Morris |
Transgenic |
BALB/c |
| mesothelin -/- knockout |
mesothelin |
Pastan |
Null |
C57BL/6 |
| CAS +/- knockout |
Cse1l |
Pastan |
Null |
129 |
| TRalphaPV mouse |
Thyroid hormone receptor alphaPV |
Cheng |
Knock-in |
Mixed Genetic Background |
| TRbetaPV mouse |
Thyroid hormone receptor beta |
Cheng |
Knock-in |
Mixed Genetic Background |
| TRbetaPV, SRC-1 KO |
Thyroid hormone receptor beta, steroid hormone receptor coactivator-1 |
Cheng |
Knock-in |
Mixed Genetic Background |
| TRbeta PV, TRbeta KO |
Thyroid hormone receptor beta |
Cheng |
Knock-in |
Mixed Genetic Background |
| ob/ob |
Leptin (obese spontaneous mutation) |
Gonzalez |
Other |
C57BL/6 |
| ALB-rtTA-transgenic |
Albumin-reverse Tetracyline transactivator |
Gonzalez |
Transgenic |
Mixed Genetic Background |
| C3(1)/Tag |
SV40 Large T attached to prostatic steroid-binding protein (rat) |
Gonzalez |
Transgenic |
FVB/N |
| Villin-Cre |
villin regulatory sequence linked to Cre recombinase |
Gonzalez |
Transgenic |
Mixed Genetic Background |
| CAGGCre-ER |
estrogen receptor Cre recombinase linked to cagg promoter sequence |
Gonzalez |
cre Transgenic |
Unknown |
| PPAR-gamma fl/fl:MxCre |
peroxisome proliferator-activated receptor-gamma:Cre recombinase under the control of alpha/beta interferon inducible (Mx) promoter |
Gonzalez |
Multiple Mutations |
C57BL/6 |
| PPAR-gamma (fl/fl) |
peroxisome proliferator-activated receptor-gamma |
Gonzalez |
Transgenic |
Mixed Genetic Background |
| PPAR-beta (knockout) |
peroxisome proliferator-activated receptor-beta |
Gonzalez |
Null |
C57BL/6 |
| 129-PPAR-alpha (knockout) |
peroxisome proliferator-activated receptor-alpha |
Gonzalez |
Null |
129 |
| ob/ob:AlbCre:PPAR-gamma (fl/fl) |
obese spontaneous mutation:Cre recombinase under the control of the Albumin promoter:peroxisome proliferator-activated receptor-gamma |
Gonzalez |
Multiple Mutations |
C57BL/6 |
| Lepr |
leptin receptor deficient |
Gonzalez |
Other |
C57BL/6 |
| CYP2E1-null |
Cytochrome P450-null |
Gonzalez |
Null |
129 |
| HNF-1-alpha |
Hepatocyte Nuclear Factor-1-alpha |
Gonzalez |
Null |
C57BL/6 |
| Arnt(fl/fl) |
aryl hydrocarbon receptor nuclear translocator |
Gonzalez |
Transgenic |
C57BL/6 |
| ARNT(fl/fl):MxCre |
aryl hydrocarbon receptor nuclear translocator:Cre recombinase under the control of alpha/beta interferon inducible promoter |
Gonzalez |
Multiple Mutations |
C57BL/6 |
| CYP1A1 knockout |
Cytochrome P450 1A1 |
Gonzalez |
Null |
C57BL/6 |
| Tie/Tek2Cre |
endothelial cell specific receptor-2 |
Gonzalez |
cre Transgenic |
FVB/N |
| mEH-knockout |
microsomal epoxide hydrolase |
Gonzalez |
Null |
Mixed Genetic Background |
| mEH-knockout |
Microsomal epoxide hydrolase |
Gonzalez |
Null |
C57BL/6 |
| EIIaCre |
adenovirus EIIa promoter Cre |
Gonzalez |
cre Transgenic |
FVB/N |
| Sencar |
Sensitive to Carcinogenesis |
Gonzalez |
None |
Other |
| human CYP3A4 transgenic |
cytochrome P450 3A4 |
Gonzalez |
Transgenic |
FVB/N |
| c/ebp-alpha (fl/fl) |
CCAAT/enhancer binding protein |
Gonzalez |
Transgenic |
129 |
| B6;129CYP1A2-knockout |
cytochrome P450 1A2 |
Gonzalez |
Null |
Mixed Genetic Background |
| CYP1B1-knockout |
cytochrome P450 1B1 |
Gonzalez |
Null |
Mixed Genetic Background |
| AlbCre |
Cre recombinase under the control of the albumin promoter |
Gonzalez |
cre Transgenic |
FVB/N |
| MxCre |
alpha/beta interferon-inducible (MX) promoterCre |
Gonzalez |
cre Transgenic |
C57BL/6 |
| FxR null |
Farnesoid X-activated receptor (nuclear hormone receptor H4) |
Gonzalez |
Null |
C57BL/6 |
| FxR(fl/fl) |
Farnesoid X-activated receptor (nuclear hormone receptor H4) |
Gonzalez |
Transgenic |
C57BL/6 |
| T/ebp-knockout |
thyroid-specific enhancer-binding protein |
Kimura |
Null |
129 |
| MMTV-tTA |
Tetracycline transactivator (tTA) |
Vinson |
Transgenic |
FVB/N |
| TAL-t2 |
Tet repressor |
Vinson |
Transgenic |
C57BL/6 |
| CC10-rtTA |
rtTA |
Vinson |
Transgenic |
C57BL/6 |
| MHC-tTA |
Tetracycline transactivator (tTA) |
Vinson |
Transgenic |
FVB/N |
| Camk2-tTA |
Tetracycline transactivator (tTA) |
Vinson |
Transgenic |
C57BL/6 |
| NSE-tTA |
Tetracycline transactivator (tTA) |
Vinson |
Transgenic |
C57BL/6 |
| K5-tTA |
Tetracycline transactivator (tTA) |
Vinson |
Transgenic |
FVB/N |
| ob/ob |
Lep, ob |
Vinson |
Other |
C57BL/6 |
| c-myc [166.8] |
MYC |
Thorgeirsson |
Transgenic |
Mixed Genetic Background |
| TGF-beta [25] |
TGFB1 |
Thorgeirsson |
Transgenic |
Mixed Genetic Background |
| BOG |
RBBP-9 |
Thorgeirsson |
Transgenic |
FVB/N |
| BOG |
RBBP-9 |
Thorgeirsson |
Null |
Mixed Genetic Background |
| c-met |
MET |
Thorgeirsson |
Other |
Mixed Genetic Background |
| DCL-1 |
Arhgap7 |
Thorgeirsson |
Null |
Mixed Genetic Background |
| Hoxb6-Cre |
none (prokaryotic) |
Mackem |
cre Transgenic |
C57BL/6 |
| Col2a1-Cre |
none (prokaryotic) |
Mackem |
cre Transgenic |
C57BL/6 |
| Adeno EIIa-Cre |
none (prokaryotic) |
Mackem |
cre Transgenic |
FVB/N |
| R26R-LacZ |
none (prokaryotic reporter gene) |
Mackem |
Knock-in |
Mixed Genetic Background |
| AP2-Cre |
none (prokaryotic) |
Mackem |
cre Transgenic |
C57BL/6 |
| Hoxb6pro-Hoxd12 |
Hoxd12 |
Mackem |
Transgenic |
FVB/N |
| Col2a1-Cre-ER(T) |
none (prokaryotic) |
Mackem |
cre Transgenic |
FVB/N |
| HoxB6-Cre-ER(T) |
none (prokaryotic) |
Mackem |
cre Transgenic |
FVB/N |
| Xt mutant (Greig cephalopolysyndactyly model) |
Gli3 |
Mackem |
Null |
Other |
| Brachyury (T) mutant |
T |
Mackem |
Null |
C57BL/6 |
| noggin-lacZ |
Nog |
Mackem |
Knock-in |
129 |
| Col2a1/lox-stop/Hoxd12 |
Hoxd12 |
Mackem |
Transgenic |
FVB/N |
| Col2a1/lox-stop/HoxD13 |
Hoxd13 |
Mackem |
Transgenic |
FVB/N |
| CAGG-Cre-ER(T) |
none (prokaryotic) |
Mackem |
cre Transgenic |
FVB/N |
| TSP1 ko |
Thrombospondin 1 (Thbs1) |
Roberts |
Null |
C57BL/6 |
| HoxB6-Cre |
Cre |
Kuehn |
cre Transgenic |
Mixed Genetic Background |
| Ahr null |
aryl hydrocarbon receptor |
Byrd |
Null |
C57BL/6 |
| HNF4-floxed |
Hepatocyte Nuclear Factor 4 [alpha] (Nuclear Receptor 2A1) |
Byrd |
Transgenic |
C57BL/6 |
| Nf1;p53cis knockout |
Nf1;Trp53cis |
Reilly |
Multiple Mutations |
C57BL/6 |
| Nf1;p53cis knockout |
Nf1;Trp53cis |
Reilly |
Multiple Mutations |
129 |
| Nf1 knockout |
Nf1 |
Reilly |
Targeted Mutation |
129 |
| Nf1 knockout |
Nf1 |
Reilly |
Targeted Mutation |
C57BL/6 |
| Nf1 knockout |
Nf1 |
Reilly |
Targeted Mutation |
Other |
| Nf1;p53cis knockout |
Nf1;Trp53cis |
Reilly |
Multiple Mutations |
Other |
| p53 knockout |
Trp53 |
Reilly |
Targeted Mutation |
129 |
| p53 knockout |
Trp53 |
Reilly |
Targeted Mutation |
C57BL/6 |
| Nf1;Nf2cis |
Nf1;Nf2cis |
Reilly |
Multiple Mutations |
C57BL/6 |
| Nf2;p53cis |
Nf2;Trp53cis |
Reilly |
Multiple Mutations |
C57BL/6 |
| Rb knockout |
Rb1 |
Reilly |
Targeted Mutation |
C57BL/6 |
| Rb-flox |
Rb1 |
Reilly |
Other |
Mixed Genetic Background |
| p53-flox |
Trp53 |
Reilly |
Other |
Mixed Genetic Background |
| Nf1-flox |
Nf1 |
Reilly |
Other |
Mixed Genetic Background |
| Pten knockout |
Pten |
Reilly |
Targeted Mutation |
C57BL/6 |
| p16 knockout |
CDKN2A |
Reilly |
Targeted Mutation |
Mixed Genetic Background |
| GFAP-GFP |
Gfap |
Reilly |
Transgenic |
Mixed Genetic Background |
| nestin-Cre |
Nes |
Reilly |
cre Transgenic |
C57BL/6 |
| lox-STOP-lox-lacZ |
ActB; lacZ |
Reilly |
Transgenic |
C57BL/6 |