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CCR-AMI Rodent List (CARL) - Model Details
Strain Information
Model Descriptor:
NT-3 knockout
Common Gene Name:
NT-3
Official Gene Name:
Neurotrophin-3
Mutation Type:
Null
Strain Background:
C57BL/6
Species:
Mouse
Phenotype:
Severe peripheral sensory and sympathetic neuronal losses. Cardiac defects including tetralogy of Fallot. Die immediatly after birth.
References:
Pubmed ID:
7991545
Pubmed ID:
8841198
Additional Comments:
Proc Natl Acad Sci U S A. 1994 Dec 6;91(25):11844-8. Nat Genet. 1996 Oct;14(2):210-3
Contact Information
NCI Investigator Name:
Lino Tessarollo
Phone Number:
301-846-1202
E-mail:
tessarol@mail.nih.gov
