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CCR-AMI Rodent List (CARL) - Model Details
Strain Information
Model Descriptor:
BRCA1 humanized mice
Common Gene Name:
Brca1
Official Gene Name:
Brca1
Mutation Type:
Transgenic: Brca1 knockout
Strain Background:
Mixed Genetic Background
Species:
Mouse
Phenotype:
The embryonic lethality of Brca1 knock-out mice is rescued by a BAC transgene containing human BRCA1 gene. The rescued mice are viable and fertile
References:
Pubmed ID:
11170347
Additional Comments:
Contact Information
NCI Investigator Name:
Shyam Sharan
Phone Number:
301-846-5140
E-mail:
sharans@mail.nih.gov