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CCR-AMI Rodent List (CARL) - Model Details
Strain Information
Model Descriptor:
MMTV-CR-1
Common Gene Name:
Cripto-1
Official Gene Name:
TDGF-1
Mutation Type:
Transgenic
Strain Background:
FVB/N
Species:
Mouse
Phenotype:
Enhanced ductal side branching in mammary gland of virgin mice; ductal hyperplasias in mammary gland of nulliparous and multiparous animals; mammary papillary adenocarcinomas in ~40% of multiparous females 15-18 months old.
Additional Comments:
Contact Information
NCI Investigator Name:
David Salomon
Phone Number:
301-496-9536
E-mail:
salomond@mail.nih.gov
