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CCR-AMI Rodent List (CARL) - Model Details

Strain Information
   
Model Descriptor: LAP-tTA
Common Gene Name: tTA
Official Gene Name: tetracycline transactivator
Mutation Type: Transgenic
Strain Background: FVB/N
Species: Mouse 
   
Phenotype: Tet-regulated expression of tTA in liver (tet-off).
   
References:  
  Pubmed ID: 8855286
  Pubmed ID: 10052353
  Pubmed ID: 11381087
   
Additional Comments: LAP-tTA mice were generated by Dr. Herman Bujard (Germany) and the line was bred to FVB/N predominant background in Bruce Counklin and Michael Bishop's labs at the UCSF.
 
   
Contact Information
   
NCI Investigator Name: Ying Zhang
Phone Number: 301-496-6454
E-mail: yingz@helix.nih.gov