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CCR-AMI Rodent List (CARL) - Model Details
Strain Information
Model Descriptor:
HEL specific Ig
Common Gene Name:
Hen Egg Lysozyme specific immunoglobulin
Official Gene Name:
IghelMD4
Mutation Type:
Transgenic
Strain Background:
C57BL/6
Species:
Mouse
Phenotype:
>90% of B cells are derived from the transgene, express predominantly IgM and IgD, and are specific from Hen Egg Lysozyme
References:
Pubmed ID:
1622894
Additional Comments:
Used to study B cell tolerance. Maintained as a heterozygote by breeding with wild-type C57Bl.6 mice.
Contact Information
NCI Investigator Name:
John Schiller
Phone Number:
301-496-6539
E-mail:
schillej@dc37a.nci.nih.gov
