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CCR-AMI Rodent List (CARL) - Model Details
Strain Information
Model Descriptor:
WAP3-Int3sh
Common Gene Name:
Notch4
Official Gene Name:
Notch4
Mutation Type:
Transgenic
Strain Background:
FVB/N
Species:
Mouse
Phenotype:
Females lactate and develop mammary tumors as well as tumors of organs that express WAP during pregnancy.
Additional Comments:
The RAM23 region of the intracellular domain of human Notch4 has been deleted.
Contact Information
NCI Investigator Name:
Robert Callahan
Phone Number:
301-496-9871
E-mail:
callahro@mail.nih.gov