Our Science – Zhu Website
Zhongyu Zhu, Ph.D.
Antibodies are a key component of the immune system, playing a central role in antigen/pathogen recognition and stimulation of immune response, and also functioning as a huge collection of naturally produced medicine targeting various diseases.
Our research interests focus on antibody-based therapeutics development through phage and yeast display antibody library technology. Working together with our collaborators, we are particularly interested in the following three categories:
1) Naked Antibody: Full-size antibody can serve as a modulator of disease-causing protein-protein interactions and mediator of immune responses toward disease targets for drug development.
2) Antibody-Drug Conjugates (ADCs): ADCs provide biomarker-targeted delivery of toxic drug for cancer therapy.
3) Chimeric Antigen Receptors (CARs): Engineered antibody fragment can be expressed as CARs on T cells for cancer biomarker-targeted T cell-based immunotherapy.
This page was last updated on 5/29/2014.