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Xiao-jiang Gao, Ph.D.
1. Characterization of the genetic diversity of HLA genes. High resolution and large throughput molecular gene typing for class I and class II HLA genes for disease cohorts have become a prerequisite for understanding the role played by these highly polymorphic immunogenetic genes. Inherited genetic variations at the nucleotide as well as peptide level provide crucial information to the understanding of disease pathogenesis.
2. Interaction between MHC and KIR and its impact on cancer and infectious disease. Investigation of both MHC and KIR genes provides insights into the synergistic interaction between the two highly polymorphic immunogenetic systems and its relevance to cancer and infectious diseases and lead to an overall understanding of the cross-passing between the acquired immunity and innate immunity.
This page was last updated on 2/26/2013.