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Masanori Onda, M.D., Ph.D.

Laboratory of Molecular Biology
Molecular Biology Section
Staff Scientist
Center for Cancer Research
National Cancer Institute
Building 37, Room 5110
Bethesda, MD 20892


Dr. Onda is staff scientist in the Laboratory Molecular Biology, Center for Cancer Research. He obtained his M.D. in 1989. He obtained his Ph.D. from the University of Tokyo in 1997. He received medical training (orthopedic surgery) at the University of Tokyo, Hitachi General Hospital, and Mitsui Memorial Hospital. He received research training at the Institute of Medical Science, University of Tokyo, and at NIH.


New Approach to Cancer Therapy: Recombinant Immunotoxins
- Reducing the immunogenicity of protein therapeutics
- Reducing the immunogenicity of PE38-based immunotoxins
- Identification of human B lymphocyte epitopes

New Target for Mesothelioma and Gynecological Malignancies: Mesothelin
- Soluble mesothelin is a useful biomarker for mesothelioma
- New antibody for mesothelin and MPF

Investigating New Molecular Targets for Immunotoxin (CAPC, PATE, etc.)

New target for Osteosarcoma and Neuroblastoma:
- 8H9 immunotoxin

New Target for Lymphoma:
- CD30 immunotoxin
- CD30 antibody, which does not bind shedding epitopes

This page was last updated on 7/14/2014.