Our Science – Lucas Website

Philip J Lucas, Ph.D.

Experimental Transplantation and Immunology Branch Transplantation Immunology Section Staff Scientist Center for Cancer Research National Cancer Institute Bldg. 10, CRC Room 3-3288 Bethesda, MD 20892-1203 Phone:   301-435-3542 Fax:   301-480-4354 E-Mail:   lucasp@mail.nih.gov

Biography

BS,The Pennsylvania State University 1982
Microbiology and Molecular Biology
PhD, The George Washington University 1991
Microbiology and Immunology
Fellow, Washington University, Saint Louis, MO 1991
Mentor Dr. Dennis Loh
Fellow, NIH, Experimental Immunology Branch 1995
Mentor Dr. Ronald Gress
Staff Scientist, NIH, Experimental Transpl & Immunology Branch 2000

Research

My major research interest is understanding T cell homeostasis and the signals involved in communicating peripheral T cells status to the thymus. It is well known that the number and type of T cell is tightly regulated through a complex network of chemokines, hormones, cytokines and cell-cell interactions. Disruption of T cell homeostasis by altering T cell numbers in the peripheral immune system has been a useful tool in understanding the multitude of signals involved in peripheral T cell homeostasis. We are using similar methods to identify which of these signals are necessary to modify T cell output from the thymus.

This page was last updated on 2/27/2013.