Our Science – Hickstein Website
Dennis D. Hickstein, M.D.
Molecular Oncology and Gene Transfer
The research in our laboratory involves two areas of investigations. The first area of study focuses on the correction of the disease phenotype in three genetic immunodeficiency diseases-leukocyte adhesion deficiency type 1, GATA2 deficiency, and DOCK8 deficiency-using two approaches: allogeneic hematopoietic stem cell transplantation and gene transfer into hematopoietic stem cells. These studies are designed to achieve long-term correction of hematopoietic stem cells. In the second area of study, we are developing zebrafish models of human blood diseases, particularly a zebrafish model of GATA2 deficiency.
This page was last updated on 12/9/2013.