Our Science – Walters Website
Kylie J. Walters, Ph.D.
Projects in the Walters lab focus on how proteins are removed from cells. We are interested in how misfolded protein substrates are recognized and ubiquitinated by cellular surveillance systems and how ubiquitinated substrates are identified and processed by proteasome. We use a variety of biophysical techniques, our most powerful of which is NMR spectroscopy, to help develop a mechanistic understanding of how proteasome recognizes and processes its substrates. Our long-term goal is the manipulation of this process for proteins of interest, including oncoproteins and tumor suppressors.
This page was last updated on 4/10/2014.