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Christophe E. Redon, Ph.D.

Portait Photo of Christophe Redon
Developmental Therapeutics Branch
Chromatin Structure and Function Group
Staff Scientist
Center for Cancer Research
National Cancer Institute
Bldg 37, Room 5050
Bethesda, MD 20892
Phone:  
301-451-8576
Fax:  
301-402-0752
E-Mail:  
REDONC@MAIL.NIH.GOV

Biography

Dr Redon studied in France and completed his PhD from the University of Reims Champagne Ardenne (Biochemistry and Cellular Biology, study of the grapevine histones). While he started his scientific career as a plant biologist, the following years were dedicated to cancer biology and DNA repair. However, the focus of his research is still devoted, in part, to the study of histones. In 1999, Dr Redon joined Dr Bonner laboratory at the National Institutes of Health (Laboratory of Molecular Pharmacology) as a Visiting Fellow where he was appointed as Staff Scientist in 2010. Upon his arrival at NIH, Dr Redon studied the role of the histone H2AX in genome stability, looked into the link between chronic inflammation and cancer, analyzed cellular pathways involved in DNA repair, and investigated the mechanism of action of new cancer drugs. In the last 4 years, Dr Redon has developed the use of gamma-H2AX (a marker for DNA double-strand break) in the clinic.

Research

Cellular Biologist specializing in DNA repair mechanisms with more than 15 years of laboratory experience and 60 publications. Recipient of the 2007 NCI Director Innovation Award and three Federal Technology Transfer Awards. Research interests centered on the DNA damage repair, genomic instability, radiation biology and cancer and covering both basic research projects and translational studies. Author of publications related to new techniques, the DNA damage response and cancer drug discovery. Published research papers and reviews in different background journals and books some achieved with extending collaborations with other research teams in Australia, Europe or the USA. Participated in the design of tools for the detection of DNA damage. Co-designed a pilot project to investigate a new putative Cancer Biomarker. Participated in the development of an assay for a new pharmacodynamic biomarker in response to therapeutic treatments. Currently developing a sensitive and accurate biomarker for exposure to radiation and genotoxic drugs. Mentor for the summer student program as well as for graduate students, PhD student and postdoctoral fellows.

This page was last updated on 3/12/2014.