Our Science – Shukla Website
Suneet Shukla, Ph.D.
Selected Publications |
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| 1)
Ansbro MR, Shukla S, Ambudkar SV, Yuspa SH, Li L. Screening Compounds with a Novel High-Throughput ABCB1-Mediated Efflux Assay Identifies Drugs with Known Therapeutic Targets at Risk for Multidrug Resistance Interference. PLoS ONE. 8: e60334, 2013. [Journal] |
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| 2)
Duveau DY, Hu X, Walsh MJ, Shukla S, Skoumbourdis AP, Boxer MB, Ambudkar SV, Shen M, Thomas CJ. Synthesis and biological evaluation of analogues of the kinase inhibitor nilotinib as Abl and Kit inhibitors. Bioorg. Med. Chem. Lett. 23: 682-6, 2013. [Journal] |
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| 3)
Sen R, Natarajan K, Bhullar J, Shukla S, Fang HB, Cai L, Chen ZS, Ambudkar SV, Baer MR. The novel BCR-ABL and FLT3 inhibitor ponatinib is a potent inhibitor of the multidrug resistance-associated ATP-binding cassette transporter ABCG2. Molecular cancer therapeutics. 2012. [Journal] |
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| 4)
Natarajan K, Bhullar J, Shukla S, Burcu M, Chen ZS, Ambudkar SV, Baer MR. The Pim kinase inhibitor SGI-1776 decreases cell surface expression of P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) and drug transport by Pim-1-dependent and -independent mechanisms. Biochem. Pharmacol. 2012. [Journal] |
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| 5)
Shukla S, Chen ZS, Ambudkar SV. Tyrosine kinase inhibitors as modulators of ABC transporter-mediated drug resistance. Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy. 2012. [Journal] |
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| 6)
Shukla S, Schwartz C, Kapoor K, Kouanda A, Ambudkar SV. Use of Baculovirus BacMam Vectors for Expression of ABC Drug Transporters in Mammalian Cells. Drug Metab. Dispos. 40: 304-12, 2012. [Journal] |
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| 7)
Kannan P, Telu S, Shukla S, Ambudkar SV, Pike VW, Halldin C, Gottesman MM, Innis RB, Hall MD. The "Specific" P-Glycoprotein Inhibitor Tariquidar Is Also a Substrate and an Inhibitor for Breast Cancer Resistance Protein (BCRP/ABCG2). ACS Chem Neurosci. 2: 82-9, 2011. [Journal] |
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| 8)
Shukla S, Ohnuma S, Ambudkar SV. Improving cancer chemotherapy with modulators of ABC drug transporters. Curr Drug Targets. 12: 621-30, 2011. [Journal] |
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| 9)
Shukla S, Skoumbourdis AP, Walsh MJ, Hartz AM, Fung KL, Wu CP, Gottesman MM, Bauer B, Thomas CJ, Ambudkar SV. Synthesis and characterization of a BODIPY conjugate of the BCR-ABL kinase inhibitor Tasigna (nilotinib): evidence for transport of Tasigna and its fluorescent derivative by ABC drug transporters. Mol. Pharm. 8: 1292-302, 2011. [Journal] |
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| 10)
Shi Z, Tiwari AK, Shukla S, Robey RW, Singh S, Kim IW, Bates SE, Peng X, Abraham I, Ambudkar SV, Talele TT, Fu LW, Chen ZS. Sildenafil reverses ABCB1- and ABCG2-mediated chemotherapeutic drug resistance. Cancer Res. 71: 3029-41, 2011. [Journal] |
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This page was last updated on 4/22/2013.
