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Our Science – Waheed Website

Abdul A. Waheed, Ph.D.

Selected Publications

1)  Zhang H, Curreli F, Waheed A, Mercredi P, Mehta M, Bhargava P, Scacalossi D, Tong X, Lee S, Cooper A, Summers M, Freed E, Debnath A.
Dual-acting stapled peptides target both HIV-1 entry and assembly.
Retrovirology. 10: 136, 2013.
Full Text Article. [Journal]
2)  Waheed AA, Ablan SD, Roser JD, Sowder RC, Schaffner CP, Chertova E, Freed EO.
HIV-1 escape from the entry-inhibiting effects of a cholesterol-binding compound via cleavage of gp41 by the viral protease.
Proc. Natl. Acad. Sci. U.S.A. 104: 8467-71, 2007.
3)  Waheed AA, Ablan SD, Mankowski MK, Cummins JE, Ptak RG, Schaffner CP, Freed EO.
Inhibition of HIV-1 replication by amphotericin B methyl ester: selection for resistant variants.
J. Biol. Chem. 281: 28699-711, 2006.
4)  Johnson EN, Seasholtz TM, Waheed AA, Kreutz B, Suzuki N, Kozasa T, Jones TL, Brown JH, Druey KM.
RGS16 inhibits signalling through the G alpha 13-Rho axis.
Nat. Cell Biol. 5: 1095-103, 2003.
5)  Waheed AA, Shimada Y, Heijnen HF, Nakamura M, Inomata M, Hayashi M, Iwashita S, Slot JW, Ohno-Iwashita Y.
Selective binding of perfringolysin O derivative to cholesterol-rich membrane microdomains (rafts).
Proc. Natl. Acad. Sci. U.S.A. 98: 4926-31, 2001.
6)  Daniels SI, Soule EE, Davidoff KS, Bernbaum JG, Hu D, Maeda K, Stahl SJ, Naiman NE, Waheed AA, Freed EO, Wingfield P, Yarchoan R, Davis DA.
Activation of virus uptake through induction of macropinocytosis with a novel polymerizing peptide.
FASEB J. 28: 106-16, 2014.
7)  Waheed AA, Freed EO.
HIV Type 1 Gag as a Target for Antiviral Therapy.
AIDS Res. Hum. Retroviruses. 28: 54-75, 2012.
8)  Waheed AA, Brass AL, Gummuluru S, Tachedjian G.
Host-pathogen interactions of retroviruses.
Mol Biol Int. 2012: 648512, 2012.
9)  Zhang H, Curreli F, Zhang X, Bhattacharya S, Waheed AA, Cooper A, Cowburn D, Freed EO, Debnath AK.
Antiviral activity of alpha-helical stapled peptides designed from the HIV-1 capsid dimerization domain.
Retrovirology. 8: 28, 2011.
10)  Kim SE, Liu F, Im YJ, Stephen AG, Fivash MJ, Waheed AA, Freed EO, Fisher RJ, Hurley JH, Burke TR.
Elucidation of New Binding Interactions with the Tumor Susceptibility Gene 101 (Tsg101) Protein Using Modified HIV-1 Gag-p6 Derived Peptide Ligands.
ACS medicinal chemistry letters. 2: 337-341, 2011.
11)  Waheed AA, Ablan SD, Sowder RC, Roser JD, Schaffner CP, Chertova E, Freed EO.
Effect of mutations in the human immunodeficiency virus type 1 protease on cleavage of the gp41 cytoplasmic tail.
J. Virol. 84: 3121-6, 2010.
12)  Waheed AA, Freed EO.
The Role of Lipids in Retrovirus Replication.
Viruses. 2: 1146-1180, 2010.
13)  Liu F, Stephen AG, Waheed AA, Freed EO, Fisher RJ, Burke TR.
Application of ring-closing metathesis macrocyclization to the development of Tsg101-binding antagonists.
Bioorg. Med. Chem. Lett. 2009.
14)  Waheed AA, Freed EO.
Lipids and membrane microdomains in HIV-1 replication.
Virus Res. 143: 162-76, 2009.
15)  Liu F, Stephen A, Waheed A, Freed E, Fisher R, Burke T.
Macrocyclic peptide-peptoid hybrids designed as PPII helix mimetics (Proceedings of the 21st American Peptide Symposium).
Lebl M, eds.
Volume Jun 7-12, 2009, Bloomington, IN, USA. p. 102-103. [Meeting Proceeding]
16)  Waheed AA, Ono A, Freed EO.
Methods for the Study of HIV-1 Assembly.
Methods Mol. Biol. 485: 163-84, 2009.
17)  Waheed AA, Freed EO.
Peptide Inhibitors of HIV-1 Egress.
ACS Chem. Biol. 3: 745-747, 2008.
18)  Waheed AA, Ablan SD, Soheilian F, Nagashima K, Ono A, Schaffner CP, Freed EO.
Inhibition of Human Immunodeficiency Virus Type 1 Assembly and Release by the Cholesterol-binding Compound Amphotericin B Methyl Ester: Evidence for Vpu Dependence.
J. Virol. 2008.
19)  Liu F, Stephen AG, Waheed AA, Aman MJ, Freed EO, Fisher RJ, Burke TR.
SAR by oxime-containing peptide libraries: application to Tsg101 ligand optimization.
Chembiochem. 9: 2000-4, 2008.
20)  Zhang H, Zhao Q, Bhattacharya S, Waheed AA, Tong X, Hong A, Heck S, Curreli F, Goger M, Cowburn D, Freed EO, Debnath AK.
A cell-penetrating helical peptide as a potential HIV-1 inhibitor.
J. Mol. Biol. 378: 565-80, 2008.
21)  Waheed AA, Freed EO.
Influenza virus not cRAFTy enough to dodge viperin.
Cell Host Microbe. 2: 71-2, 2007.
22)  Nini L, Waheed AA, Panicker LM, Czapiga M, Zhang JH, Simonds WF.
R7-binding protein targets the G protein beta 5/R7-regulator of G protein signaling complex to lipid rafts in neuronal cells and brain.
BMC Biochem. 8: 18, 2007.
23)  Ono A, Waheed AA, Freed EO.
Depletion of cellular cholesterol inhibits membrane binding and higher-order multimerization of human immunodeficiency virus type 1 Gag.
Virology. 360: 27-35, 2007.
24)  Berkane AA, Nguyen HT, Tranchida F, Waheed AA, Deyris V, Tchiakpe L, Fasano C, Nicoletti C, Desseaux V, Ajandouz el H, Comeau D, Comeau L, Hiol A.
Proteomic of lipid rafts in the exocrine pancreas from diet-induced obese rats.
Biochem. Biophys. Res. Commun. 355: 813-9, 2007.
25)  Nguyen HT, Amine AB, Lafitte D, Waheed AA, Nicoletti C, Villard C, Létisse M, Deyris V, Rozière M, Tchiakpe L, Danielle CD, Comeau L, Hiol A.
Proteomic characterization of lipid rafts markers from the rat intestinal brush border.
Biochem. Biophys. Res. Commun. 342: 236-44, 2006.
26)  Osterhout JL, Waheed AA, Hiol A, Ward RJ, Davey PC, Nini L, Wang J, Milligan G, Jones TL, Druey KM.
Palmitoylation regulates regulator of G-protein signaling (RGS) 16 function. II. Palmitoylation of a cysteine residue in the RGS box is critical for RGS16 GTPase accelerating activity and regulation of Gi-coupled signalling.
J. Biol. Chem. 278: 19309-16, 2003.
27)  Shimada Y, Inomata M, Suzuki H, Hayashi M, Abdul Waheed A, Ohno-Iwashita Y.
Separation of a cholesterol-enriched microdomain involved in T-cell signal transduction.
FEBS J. 272: 5454-63, 2005.
28)  Ono A, Waheed AA, Joshi A, Freed EO.
Association of human immunodeficiency virus type 1 gag with membrane does not require highly basic sequences in the nucleocapsid: use of a novel Gag multimerization assay.
J. Virol. 79: 14131-40, 2005.
29)  Ohno-Iwashita Y, Shimada Y, Waheed AA, Hayashi M, Inomata M, Nakamura M, Maruya M, Iwashita S.
Perfringolysin O, a cholesterol-binding cytolysin, as a probe for lipid rafts.
Anaerobe. 10: 125-34, 2004.
30)  Waheed A, Gupta P.
Biological membranes: Structure and function. In: Biochemistry (LM Srivastava and N Das, eds).
New Delhi: CBS Publishers and Distributors; 2004. p. 15-32 [Book Chapter]
31)  Waheed AA.
Citation rate unrelated to journals' impact factors.
Nature. 426: 495, 2003.
32)  Nakamura M, Kondo H, Shimada Y, Waheed AA, Ohno-Iwashita Y.
Cellular aging-dependent decrease in cholesterol in membrane microdomains of human diploid fibroblasts.
Exp. Cell Res. 290: 381-90, 2003.
33)  Heijnen HF, Van Lier M, Waaijenborg S, Ohno-Iwashita Y, Waheed AA, Inomata M, Gorter G, Möbius W, Akkerman JW, Slot JW.
Concentration of rafts in platelet filopodia correlates with recruitment of c-Src and CD63 to these domains.
J. Thromb. Haemost. 1: 1161-73, 2003.
34)  Hiol A, Davey PC, Osterhout JL, Waheed AA, Fischer ER, Chen CK, Milligan G, Druey KM, Jones TL.
Palmitoylation regulates regulators of G-protein signaling (RGS) 16 function. I. Mutation of amino-terminal cysteine residues on RGS16 prevents its targeting to lipid rafts and palmitoylation of an internal cysteine residue.
J. Biol. Chem. 278: 19301-8, 2003.
35)  Waheed AA, Jones TL.
Hsp90 interactions and acylation target the G protein Galpha 12 but not Galpha 13 to lipid rafts.
J. Biol. Chem. 277: 32409-12, 2002.
36)  Waheed A, Gupta P.
Estimation of protein using eosin B dye- A new method. In: Practical Biochemistry.
New Delhi: CBS Publishers and Distributors (LM Srivastava and N Das, eds); 2001. p. 70-75 [Book Chapter]
37)  Waheed AA.
Scientists turn to journals in English.
ScientificWorldJournal. 1: 239-40, 2001.
38)  Waheed AA, Rao KS, Gupta PD.
Mechanism of dye binding in the protein assay using eosin dyes.
Anal. Biochem. 287: 73-9, 2000.
39)  Waheed AA.
England and US corner the journal market.
Nature. 405: 613, 2000.
40)  Waheed AA, Gupta PD.
Estimation of submicrogram quantities of protein using the dye eosin Y.
J. Biochem. Biophys. Methods. 42: 125-32, 2000.
41)  Waheed AA, Gupta PD.
Single-step method for estimating nanogram quantities of protein.
Anal. Biochem. 275: 124-7, 1999.
42)  Waheed AA, Toyama Y, Yasuzumi F, Gupta PD.
Decreased densities of intramembranous particles and cytochemically detectable cholesterol in microvilli of starved rat enterocytes.
Cell Biol. Int. 22: 177-83, 1998.
43)  Waheed AA, Yasuzumi F, Gupta PD.
Lipid and fatty acid composition of brush border membrane of rat intestine during starvation.
Lipids. 33: 1093-7, 1998.
44)  Waheed AA, Gupta PD.
Changes in structural and functional properties of rat intestinal brush border membrane during starvation.
Life Sci. 61: 2425-33, 1997.
45)  Waheed AA, Gupta PD.
Application of an eosin B dye method for estimating a wide range of proteins.
J. Biochem. Biophys. Methods. 33: 187-96, 1996.
46)  Waheed AA, Gupta PD.
Estimation of protein using eosin B dye.
Anal. Biochem. 233: 249-52, 1996.
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This page was last updated on 3/28/2014.