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Our Science – Baba Website

Masaya Baba, M.D., Ph.D.

Selected Publications

1)  Hasumi H, Baba M, Hasumi Y, Huang Y, Oh HF, Hughes RM, Klein ME, Takikita S, Nagashima K, Schmidt LS, Linehan WM.
Regulation of Mitochondrial Oxidative Metabolism by Tumor Suppressor FLCN.
J Natl Cancer Inst. in press, 2012.
[Journal]
2)  Baba M, Keller JR, Sun HW, Resch W, Kuchen S, Suh HC, Hasumi H, Hasumi Y, Kieffer-Kwon KR, Gonzalez CG, Hughes RM, Klein ME, Oh HF, Bible P, Southon E, Tessarollo L, Schmidt LS, Linehan WM, Casellas R.
The folliculin-FNIP1 pathway deleted in human Birt-Hogg-Dube syndrome is required for murine B-cell development.
Blood. 120: 1254-61, 2012.
[Journal]
3)  Benhammou JN, Vocke CD, Santani A, Schmidt LS, Baba M, Seyama K, Wu X, Korolevich S, Nathanson KL, Stolle CA, Linehan WM.
Identification of intragenic deletions and duplication in the FLCN gene in Birt-Hogg-Dube syndrome.
Genes Chromosomes Cancer. 50: 466-77, 2011.
[Journal]
4)  Hong SB, Oh H, Valera VA, Baba M, Schmidt LS, Linehan WM.
Inactivation of the FLCN tumor suppressor gene induces TFE3 transcriptional activity by increasing its nuclear localization.
PLoS ONE. 5: e15793, 2010.
[Journal]
5)  Hong SB, Oh H, Valera VA, Stull J, Ngo DT, Baba M, Merino MJ, Linehan WM, Schmidt LS.
Tumor suppressor FLCN inhibits tumorigenesis of a FLCN-null renal cancer cell line and regulates expression of key molecules in TGF-beta signaling.
Mol. Cancer. 9: 160, 2010.
[Journal]
6)  Hasumi Y, Baba M, Ajima R, Hasumi H, Valera VA, Klein ME, Haines DC, Merino MJ, Hong SB, Yamaguchi TP, Schmidt LS, Linehan WM.
Homozygous loss of BHD causes early embryonic lethality and kidney tumor development with activation of mTORC1 and mTORC2.
Proc. Natl. Acad. Sci. U.S.A. 106: 18722-7, 2009.
[Journal]
7)  Yao M, Huang Y, Shioi K, Hattori K, Murakami T, Sano F, Baba M, Kondo K, Nakaigawa N, Kishida T, Nagashima Y, Yamada-Okabe H, Kubota Y.
A three-gene expression signature model to predict clinical outcome of clear cell renal carcinoma.
Int. J. Cancer. 123: 1126-32, 2008.
[Journal]
8)  Hasumi H, Baba M, Hong SB, Hasumi Y, Huang Y, Yao M, Valera VA, Linehan WM, Schmidt LS.
Identification and characterization of a novel folliculin-interacting protein FNIP2.
Gene. 415: 60-7, 2008.
[Journal]
9)  Baba M, Furihata M, Hong SB, Tessarollo L, Haines DC, Southon E, Patel V, Igarashi P, Alvord WG, Leighty R, Yao M, Bernardo M, Ileva L, Choyke P, Warren MB, Zbar B, Linehan WM, Schmidt LS.
Kidney-targeted Birt-Hogg-Dube gene inactivation in a mouse model: Erk1/2 and Akt-mTOR activation, cell hyperproliferation, and polycystic kidneys.
J. Natl. Cancer Inst. 100: 140-54, 2008.
[Journal]
10)  Hattori K, Teranishi J, Stolle C, Yoshida M, Kondo K, Kishida T, Kanno H, Baba M, Kubota Y, Yao M.
Detection of germline deletions using real-time quantitative polymerase chain reaction in Japanese patients with von Hippel-Lindau disease.
Cancer Sci. 97: 400-5, 2006.
[Journal]
Click Here to View Expanded Bibliography.

This page was last updated on 9/8/2012.