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Our Science – Khanna Website

Chand Khanna, D.V.M., Ph.D.

Selected Publications

1)  El Touny LH, Vieira A, Mendoza A, Khanna C, Hoenerhoff MJ, Green JE.
Combined SFK/MEK inhibition prevents metastatic outgrowth of dormant tumor cells.
J. Clin. Invest. 124: 156-68, 2014.
[Journal]
2)  Paoloni M, Webb C, Mazcko C, Cherba D, Hendricks W, Lana S, Ehrhart EJ, Charles B, Fehling H, Kumar L, Vail D, Henson M, Childress M, Kitchell B, Kingsley C, Kim S, Neff M, Davis B, Khanna C, Trent J.
Prospective molecular profiling of canine cancers provides a clinically relevant comparative model for evaluating personalized medicine (PMed) trials.
PLoS ONE. 9: e90028, 2014.
[Journal]
3)  Heinecke JL, Ridnour LA, Cheng RY, Switzer CH, Lizardo MM, Khanna C, Glynn SA, Hussain SP, Young HA, Ambs S, Wink DA.
Tumor microenvironment-based feed-forward regulation of NOS2 in breast cancer progression.
Proc. Natl. Acad. Sci. U.S.A. 111: 6323-8, 2014.
[Journal]
4)  Mendoza A, Gharpure R, Dennis J, Webster JD, Smedley J, Khanna C.
A novel noninvasive method for evaluating experimental lung metastasis in mice.
J. Am. Assoc. Lab. Anim. Sci. 52: 584-9, 2013.
[Journal]
5)  Savage SA, Mirabello L, Wang Z, Gastier-Foster JM, Gorlick R, Khanna C, Flanagan AM, Tirabosco R, Andrulis IL, Wunder JS, Gokgoz N, Patiño-Garcia A, Sierrasesúmaga L, Lecanda F, Kurucu N, Ilhan IE, Sari N, Serra M, Hattinger C, Picci P, Spector LG, Barkauskas DA, Marina N, de Toledo SR, Petrilli AS, Amary MF, Halai D, Thomas DM, Douglass C, Meltzer PS, Jacobs K, Chung CC, Berndt SI, Purdue MP, Caporaso NE, Tucker M, Rothman N, Landi MT, Silverman DT, Kraft P, Hunter DJ, Malats N, Kogevinas M, Wacholder S, Troisi R, Helman L, Fraumeni JF, Yeager M, Hoover RN, Chanock SJ.
Genome-wide association study identifies two susceptibility loci for osteosarcoma.
Nat. Genet. 45: 799-803, 2013.
[Journal]
6)  Yeung CL, Ngo VN, Grohar PJ, Arnaldez FI, Asante A, Wan X, Khan J, Hewitt SM, Khanna C, Staudt LM, Helman LJ.
Loss-of-function screen in rhabdomyosarcoma identifies CRKL-YES as a critical signal for tumor growth.
Oncogene. 32: 5429-38, 2013.
[Journal]
7)  Guha M, Srinivasan S, Ruthel G, Kashina AK, Carstens RP, Mendoza A, Khanna C, Van Winkle T, Avadhani NG.
Mitochondrial retrograde signaling induces epithelial-mesenchymal transition and generates breast cancer stem cells.
Oncogene. [Epub ahead of print], 2013.
[Journal]
8)  Hong SH, Ren L, Mendoza A, Eleswarapu A, Khanna C.
Apoptosis resistance and PKC signaling: distinguishing features of high and low metastatic cells.
Neoplasia. 14: 249-58, 2012.
[Journal]
9)  Ren L, Hong SH, Chen QR, Briggs J, Cassavaugh J, Srinivasan S, Lizardo MM, Mendoza A, Xia AY, Avadhani N, Khan J, Khanna C.
Dysregulation of ezrin phosphorylation prevents metastasis and alters cellular metabolism in osteosarcoma.
Cancer Res. 72: 1001-12, 2012.
[Journal]
10)  Schayek H, Bentov I, Jacob-Hirsch J, Yeung C, Khanna C, Helman LJ, Plymate SR, Werner H.
Global methylation analysis identifies PITX2 as an upstream regulator of the androgen receptor and IGF-I receptor genes in prostate cancer.
Horm. Metab. Res. 44: 511-9, 2012.
[Journal]
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This page was last updated on 5/7/2014.