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Our Science – Lewis Website

Dale E. Lewis, Ph.D.

Selected Publications

1)  Mazumder A, Bandyopadhyay S, Dhar A, Lewis DE, Deb S, Dey S, Chakrabarti P, Roy S.
A genetic network that balances two outcomes utilizes asymmetric recognition of operator sites.
Biophys. J. 102: 1580-9, 2012.
2)  Csiszovszki Z, Lewis DE, Le P, Sneppen K, Semsey S.
Specific contacts of the -35 region of the galP1 promoter by RNA polymerase inhibit GalR-mediated DNA looping repression.
Nucleic Acids Res. 40: 10064-72, 2012.
3)  Zurla C, Manzo C, Dunlap D, Lewis DE, Adhya S, Finzi L.
Direct demonstration and quantification of long-range DNA looping by the lambda bacteriophage repressor.
Nucleic Acids Res. 37: 2789-95, 2009.
4)  Lewis DE, Komissarova N, Le P, Kashlev M, Adhya S.
DNA Sequences in gal Operon Override Transcription Elongation Blocks.
J. Mol. Biol. 2008.
5)  Lee SJ, Lewis DE, Adhya S.
Induction of the galactose enzymes in Escherichia coli is independent of the C-1-hydroxyl optical configuration of the inducer D-galactose.
J. Bacteriol. 190: 7932-8, 2008.
6)  Lia G, Semsey S, Lewis DE, Adhya S, Bensimon D, Dunlap D, Finzi L.
The antiparallel loops in gal DNA.
Nucleic Acids Res. 36: 4204-10, 2008.
7)  Zurla C, Franzini A, Galli G, Dunlap D, Lewis D, Adhya S, Finzi L.
Novel tethered particle motion analysis of CI protein-mediated DNA looping in the regulation of bacteriophage lambda.
J. Phys.: Condens. Matter. 18: S225-S234, 2006.
8)  Lewis DE, Adhya S.
Axiom of determining transcription start points by RNA polymerase in Escherichia coli.
Mol. Microbiol. 54: 692-701, 2004.
9)  Lim HM, Lewis DE, Lee HJ, Liu M, Adhya S.
Effect of varying the supercoiling of DNA on transcription and its regulation.
Biochemistry. 42: 10718-25, 2003.
10)  Lewis DE.
Identification of promoters of Escherichia coli and phage in transcription section plasmid pSA850.
Meth. Enzymol. 370: 618-45, 2003.
11)  Lia G, Bensimon D, Croquette V, Allemand JF, Dunlap D, Lewis DE, Adhya S, Finzi L.
Supercoiling and denaturation in Gal repressor/heat unstable nucleoid protein (HU)-mediated DNA looping.
Proc. Natl. Acad. Sci. U.S.A. 100: 11373-7, 2003.
12)  Lewis DE, Adhya S.
In vitro repression of the gal promoters by GalR and HU depends on the proper helical phasing of the two operators.
J. Biol. Chem. 277: 2498-504, 2002.
13)  Semsey S, Geanacopoulos M, Lewis DE, Adhya S.
Operator-bound GalR dimers close DNA loops by direct interaction: tetramerization and inducer binding.
EMBO J. 21: 4349-56, 2002.
14)  Lewis D, Adhya S.
DNA looping and tanscription regulation.
Encyclopedia of Life Science., 2001.
15)  Geanacopoulos M, Vasmatzis G, Lewis DE, Roy S, Lee B, Adhya S.
GalR mutants defective in repressosome formation.
Genes Dev. 13: 1251-62, 1999.
16)  Lewis DE, Geanacopoulos M, Adhya S.
Role of HU and DNA supercoiling in transcription repression: specialized nucleoprotein repression complex at gal promoters in Escherichia coli.
Mol. Microbiol. 31: 451-61, 1999.
17)  Adhya S, Geanacopoulos M, Lewis DE, Roy S, Aki T.
Transcription regulation by repressosome and by RNA polymerase contact.
Cold Spring Harb. Symp. Quant. Biol. 63: 1-9, 1998.
18)  Yang J, Gunasekera A, Lavoie TA, Jin L, Lewis DE, Carey J.
In vivo and in vitro studies of TrpR-DNA interactions.
J. Mol. Biol. 258: 37-52, 1996.
19)  Lewis DE, Carey J.
Analysis of trp repressor-DNA interactions using gel electrophoresis.
Electrophoresis. 14: 713-9, 1993.
20)  Carey J, Combatti N, Lewis DE, Lawson CL.
Cocrystals of Escherichia coli trp repressor bound to an alternative operator DNA sequence.
J. Mol. Biol. 234: 496-8, 1993.
21)  Carey J, Lewis DE, Lavoie TA, Yang J.
How does trp repressor bind to its operator?.
J. Biol. Chem. 266: 24509-13, 1991.
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This page was last updated on 4/10/2014.