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Our Science – Ho Website

Mitchell Ho, Ph.D.

Selected Publications

1)  Gao W, Kim H, Feng M, Phung Y, Xavier CP, Rubin JS, Ho M.
Inactivation of Wnt signaling by a human antibody that recognizes the heparan sulfate chains of glypican-3 for liver cancer therapy.
Hepatology. 2014.
[Journal]
2)  Feng M, Ho M.
Glypican-3 antibodies: a new therapeutic target for liver cancer.
FEBS Lett. 588: 377-82, 2014.
[Journal]
3)  Ray K.
Liver cancer: The promise of new approaches in the management of hepatocellular carcinoma--adding to the toolbox?.
Nat Rev Gastroenterol Hepatol. 10: 195, 2013.
[Journal]
4)  Feng M, Gao W, Wang R, Chen W, Man YG, Figg WD, Wang XW, Dimitrov DS, Ho M.
Therapeutically targeting glypican-3 via a conformation-specific single-domain antibody in hepatocellular carcinoma.
Proc. Natl. Acad. Sci. U.S.A. 110: E1083-91, 2013.
[Journal]
5)  Tang Z, Feng M, Gao W, Phung Y, Chen W, Chaudhary A, St Croix B, Qian M, Dimitrov DS, Ho M.
A human single-domain antibody elicits potent antitumor activity by targeting an epitope in mesothelin close to the cancer cell surface.
Mol. Cancer Ther. 12: 416-26, 2013.
[Journal]
6)  Kim H, Gao W, Ho M.
Novel Immunocytokine IL12-SS1 (Fv) Inhibits Mesothelioma Tumor Growth in Nude Mice.
PLoS ONE. 8: e81919, 2013.
[Journal]
7)  Gauthier A, Ho M.
Role of sorafenib in the treatment of advanced hepatocellular carcinoma: An update.
Hepatol. Res. 43: 147-54, 2013.
[Journal]
8)  Tang Z, Qian M, Ho M.
The role of mesothelin in tumor progression and targeted therapy.
Anticancer Agents Med Chem. 13: 276-80, 2013.
[Journal]
9)  Phung Y, Gao W, Man YG, Nagata S, Ho M.
High-affinity monoclonal antibodies to cell surface tumor antigen glypican-3 generated through a combination of peptide immunization and flow cytometry screening.
MAbs. 4: 592-9, 2012.
[Journal]
10)  Kim H, Phung Y, Ho M.
Changes in Global Gene Expression Associated with 3D Structure of Tumors: An Ex Vivo Matrix-Free Mesothelioma Spheroid Model.
PLoS ONE. 7: e39556, 2012.
[Journal]
Click Here to View Expanded Bibliography.

This page was last updated on 3/1/2014.