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Our Science – Freed Website

Eric O. Freed, Ph.D.

Selected Publications

1)  Chen AK, Sengupta P, Waki K, Van Engelenburg SB, Ochiya T, Ablan SD, Freed EO, Lippincott-Schwartz J.
MicroRNA binding to the HIV-1 Gag protein inhibits Gag assembly and virus production.
Proc Natl Acad Sci USA. 2014.
In Press. [Journal]
2)  Zhang H, Curreli F, Waheed A, Mercredi P, Mehta M, Bhargava P, Scacalossi D, Tong X, Lee S, Cooper A, Summers M, Freed E, Debnath A.
Dual-acting stapled peptides target both HIV-1 entry and assembly.
Retrovirology. 10: 136, 2013.
Full Text Article. [Journal]
3)  Tedbury P, Ablan S, Freed E.
Global rescue of defects in HIV-1 envelope glycoprotein incorporation: implications for matrix structure.
PLoS Pathog. 9(11): e1003739, 2013.
Full Text Article. [Journal]
4)  Afonin KA, Viard M, Martins AN, Lockett SJ, Maciag AE, Freed EO, Heldman E, Jaeger L, Blumenthal R, Shapiro BA.
Activation of different split functionalities on re-association of RNA-DNA hybrids.
Nat Nanotechnol. 8: 296-304, 2013.
5)  Keren-Kaplan T, Attali I, Estrin M, Kuo LS, Farkash E, Jerabek-Willemsen M, Blutraich N, Artzi S, Peri A, Freed EO, Wolfson HJ, Prag G.
Structure-based in silico identification of ubiquitin-binding domains provides insights into the ALIX-V:ubiquitin complex and retrovirus budding.
EMBO J. 32: 538-51, 2013.
6)  Checkley MA, Luttge BG, Mercredi PY, Kyere SK, Donlan J, Murakami T, Summers MF, Cocklin S, Freed EO.
Reevaluation of the Requirement for TIP47 in Human Immunodeficiency Virus Type 1 Envelope Glycoprotein Incorporation.
J. Virol. 87: 3561-70, 2013.
7)  Tedbury P, Freed E.
Role of matrix in HIV-1 envelope glycoprotein incorporation.
Trends Microbiol. 2014.
In Press. [Journal]
8)  Van Engelenburg S, Shtengel G, Sengupta P, Waki K, Jarnik M, Ablan S, Freed E, Hess H, Lippincott-Schwartz J.
Distribution of ESCRT machinery at HIV assembly sites reveals virus scaffolding of ESCRT subunits.
Science. 343: 343: 653-656, 2014.
Full Text Article. [Journal]
9)  Freed E, Gale M, eds.
Antiviral Innate Immunity (Part 1).
J Mol Biol. 425: 4857-5044, 2013.
Full Text Article. [Journal (Editor)]
10)  Freed E, Gale M, eds.
Antiviral Innate Immunity (Part 2).
J Mol Biol. 426: 1129-1366, 2014.
Full Text Article. [Journal (Editor)]
Click Here to View Expanded Bibliography.

This page was last updated on 6/20/2014.