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Our Science – Swing Website

Deborah A. Swing, BS, AA, RLATG

Selected Publications

1)  Xu L, Stevens J, Hilton MB, Seaman S, Conrads TP, Veenstra TD, Logsdon D, Morris H, Swing DA, Patel NL, Kalen J, Haines DC, Zudaire E, St Croix B.
COX-2 Inhibition Potentiates Antiangiogenic Cancer Therapy and Prevents Metastasis in Preclinical Models.
Sci Transl Med. 6: 242ra84, 2014.
2)  Smith S, Tripathi R, Goodings C, Cleveland S, Mathias E, Hardaway JA, Elliott N, Yi Y, Chen X, Downing J, Mullighan C, Swing DA, Tessarollo L, Li L, Love P, Jenkins NA, Copeland NG, Thompson MA, Du Y, Davé UP.
LIM Domain Only-2 (LMO2) Induces T-Cell Leukemia by Two Distinct Pathways.
PLoS ONE. 9: e85883, 2014.
3)  Arnold ES, Ling SC, Huelga SC, Lagier-Tourenne C, Polymenidou M, Ditsworth D, Kordasiewicz HB, McAlonis-Downes M, Platoshyn O, Parone PA, Da Cruz S, Clutario KM, Swing D, Tessarollo L, Marsala M, Shaw CE, Yeo GW, Cleveland DW.
ALS-linked TDP-43 mutations produce aberrant RNA splicing and adult-onset motor neuron disease without aggregation or loss of nuclear TDP-43.
Proc. Natl. Acad. Sci. U.S.A. 110: E736-45, 2013.
4)  Lee Y, Karuppagounder SS, Shin JH, Lee YI, Ko HS, Swing D, Jiang H, Kang SU, Lee BD, Kang HC, Kim D, Tessarollo L, Dawson VL, Dawson TM.
Parthanatos mediates AIMP2-activated age-dependent dopaminergic neuronal loss.
Nat. Neurosci. 16: 1392-400, 2013.
5)  Anderson MJ, Naiche LA, Wilson CP, Elder C, Swing DA, Lewandoski M.
TCreERT2, a Transgenic Mouse Line for Temporal Control of Cre-Mediated Recombination in Lineages Emerging from the Primitive Streak or Tail Bud.
PLoS ONE. 8: e62479, 2013.
6)  Berquam-Vrieze KE, Swing DA, Tessarollo L, Dupuy AJ.
Characterization of transgenic mice expressing cancer-associated variants of human NOTCH1.
Genesis. 50: 112-8, 2012.
7)  Li J, Akagi K, Hu Y, Trivett AL, Hlynialuk CJ, Swing DA, Volfovsky N, Morgan TC, Golubeva Y, Stephens RM, Smith DE, Symer DE.
Mouse endogenous retroviruses can trigger premature transcriptional termination at a distance.
Genome Res. 22: 870-84, 2012.
8)  Waldron-Roby E, Ratovitski T, Wang X, Jiang M, Watkin E, Arbez N, Graham RK, Hayden MR, Hou Z, Mori S, Swing D, Pletnikov M, Duan W, Tessarollo L, Ross CA.
Transgenic mouse model expressing the caspase 6 fragment of mutant huntingtin.
J. Neurosci. 32: 183-93, 2012.
9)  Ramonet D, Daher JP, Lin BM, Stafa K, Kim J, Banerjee R, Westerlund M, Pletnikova O, Glauser L, Yang L, Liu Y, Swing DA, Beal MF, Troncoso JC, McCaffery JM, Jenkins NA, Copeland NG, Galter D, Thomas B, Lee MK, Dawson TM, Dawson VL, Moore DJ.
Dopaminergic Neuronal Loss, Reduced Neurite Complexity and Autophagic Abnormalities in Transgenic Mice Expressing G2019S Mutant LRRK2.
PLoS ONE. 6: e18568, 2011.
10)  Tebbenkamp AT, Swing D, Tessarollo L, Borchelt DR.
Premature death and neurologic abnormalities in transgenic mice expressing a mutant huntingtin exon-2 fragment.
Hum. Mol. Genet. 20: 1633-42, 2011.
11)  Tebbenkamp AT, Green C, Xu G, Denovan-Wright EM, Rising AC, Fromholt SE, Brown HH, Swing D, Mandel RJ, Tessarollo L, Borchelt DR.
Transgenic mice expressing caspase-6-derived N-terminal fragments of mutant huntingtin develop neurologic abnormalities with predominant cytoplasmic inclusion pathology composed largely of a smaller proteolytic derivative.
Hum Mol Genet. 20: 2770-82, 2011.
12)  Smith WW, Liu Z, Liang Y, Masuda N, Swing DA, Jenkins NA, Copeland NG, Troncoso JC, Pletnikov M, Dawson TM, Martin LJ, Moran TH, Lee MK, Borchelt DR, Ross CA.
Synphilin-1 attenuates neuronal degeneration in the A53T alpha-synuclein transgenic mouse model.
Hum. Mol. Genet. 19: 2087-98, 2010.
13)  Bauer GL, Christian P, Bergsteinsdóttir K, Hallsson JH, Gísladóttir BK, Schepsky A, Swing DA, O'Sullivan TN, Arnheiter H, Bismuth K, Debbache J, Fletcher CF, Warming S, Copeland NG, Jenkins NA, Steingrímsson E.
The Role of MITF Phosphorylation Sites During Coat Color and Eye Development in Mice Analyzed by BAC Transgene Rescue.
Genetics. 183: 581-94, 2009.
14)  Crimmins S, Sutovsky M, Chen P, Huffman A, Wheeler C, Swing DA, Roth K, Wilson J, Sutovsky P, Wilson S.
Transgenic rescue of ataxia mice reveals a male-specific sterility defect.
Dev Biol. 325: 33-42, 2008.
15)  Swing DA, Sharan SK.
BAC rescue: a tool for functional analysis of the mouse genome.
Methods Mol. Biol. 256: 183-98, 2004.
16)  Sharan SK, Pyle A, Coppola V, Babus J, Swaminathan S, Benedict J, Swing D, Martin BK, Tessarollo L, Evans JP, Flaws JA, Handel MA.
BRCA2 deficiency in mice leads to meiotic impairment and infertility.
Development. 131: 131-42, 2004.
17)  O'Sullivan TN, Wu XS, Rachel RA, Huang JD, Swing DA, Matesic LE, Hammer JA, Copeland NG, Jenkins NA.
dsu functions in a MYO5A-independent pathway to suppress the coat color of dilute mice.
Proc. Natl. Acad. Sci. U.S.A. 101: 16831-6, 2004.
18)  Lee EC, Yu D, Martinez de Velasco J, Tessarollo L, Swing DA, Court DL, Jenkins NA, Copeland NG.
A highly efficient Escherichia coli-based chromosome engineering system adapted for recombinogenic targeting and subcloning of BAC DNA.
Genomics. 73: 56-65, 2001.
19)  Chandler J, Hohenstein P, Swing DA, Tessarollo L, Sharan SK.
Human BRCA1 gene rescues the embryonic lethality of Brca1 mutant mice.
Genesis. 29: 72-7, 2001.
20)  Matesic LE, Yip R, Reuss AE, Swing DA, O'Sullivan TN, Fletcher CF, Copeland NG, Jenkins NA.
Mutations in Mlph, encoding a member of the Rab effector family, cause the melanosome transport defects observed in leaden mice.
Proc. Natl. Acad. Sci. U.S.A. 98: 10238-43, 2001.
21)  Wilson SM, Yip R, Swing DA, O'Sullivan TN, Zhang Y, Novak EK, Swank RT, Russell LB, Copeland NG, Jenkins NA.
A mutation in Rab27a causes the vesicle transport defects observed in ashen mice.
Proc. Natl. Acad. Sci. U.S.A. 97: 7933-8, 2000.
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This page was last updated on 6/30/2014.