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Our Science – Rausch Website

Jason W. Rausch, Ph.D.

Selected Publications

1)  Rausch J.
Le Grice S, Goette M, eds.
Progress towards developing potent and specific inhibitors of HIV RT-associated ribonuclease H. In: Human Immunodeficiency Virus Reverse Transcriptase: A Bench-to-Bedside Success.
New York: Springer Publishing; 2013. p. 143-172 [Book Chapter]
2)  Fang X, Wang J, O'Carroll IP, Mitchell M, Zuo X, Wang Y, Yu P, Liu Y, Rausch JW, Dyba MA, Kjems J, Schwieters CD, Seifert S, Winans RE, Watts NR, Stahl SJ, Wingfield PT, Byrd RA, Le Grice SF, Rein A, Wang Y.
An Unusual Topological Structure of the HIV-1 Rev Response Element.
Cell. 155: 594-605, 2013.
Full Text Article. [Journal]
3)  Lusvarghi S, Sztuba-Solinska J, Purzycka KJ, Pauly GT, Rausch JW, Grice SF.
The HIV-2 Rev-response element: determining secondary structure and defining folding intermediates.
Nucleic Acids Res. 41: 6637-49, 2013.
4)  Rausch JW, Chelico L, Goodman MF, Le Grice SF.
Dissecting APOBEC3G substrate specificity by nucleoside analog interference.
J. Biol. Chem. 284: 7047-58, 2009.
5)  Abbondanzieri EA, Bokinsky G, Rausch JW, Zhang JX, Le Grice SF, Zhuang X.
Dynamic binding orientations direct activity of HIV reverse transcriptase.
Nature. 453: 184-9, 2008.
6)  Masaoka T, Chung S, Caboni P, Rausch J, Wilson JA, Taskent-Sezgin H, Beutler JA, Tocco G, Le Grice SF.
Exploiting drug-resistant enzymes as tools to identify thienopyrimidinone inhibitors of human immunodeficiency virus reverse transcriptase-associated ribonuclease H.
J. Med. Chem. 56: 5436-45, 2013.
7)  Lusvarghi S, Stuba-Solinska J, Purzycka K, Rausch J, Le Grice S.
RNA secondary structure prediction using high-throughput SHAPE.
J Vis Exp. 75: e50243, 2013.
Full Text Article. [Journal]
8)  Nowak E, Potrzebowski W, Konarev PV, Rausch JW, Bona MK, Svergun DI, Bujnicki JM, Le Grice SF, Nowotny M.
Structural analysis of monomeric retroviral reverse transcriptase in complex with an RNA/DNA hybrid.
Nucleic Acids Res. 41: 3874-3887, 2013.
Full Text Article. [Journal]
9)  Sztuba-Solinska J, Teramoto T, Rausch JW, Shapiro BA, Padmanabhan R, Le Grice SF.
Structural complexity of Dengue virus untranslated regions: cis-acting RNA motifs and pseudoknot interactions modulating functionality of the viral genome.
Nucleic Acids Res. 41: 5075-89, 2013.
Full Text Article. [Journal]
10)  Chung S, Himmel DM, Jiang JK, Wojtak K, Bauman JD, Rausch JW, Wilson JA, Beutler JA, Thomas CJ, Arnold E, Le Grice SF.
Synthesis, activity, and structural analysis of novel a-hydroxytropolone inhibitors of human immunodeficiency virus reverse transcriptase-associated ribonuclease H.
J. Med. Chem. 54: 4462-73, 2011.
Click Here to View Expanded Bibliography.

This page was last updated on 7/7/2014.