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Our Science – Kearney Website

Mary Kearney, Ph.D.

Selected Publications

1)  Maldarelli F, Wu X, Su L, Simonetti FR, Shao W, Hill S, Spindler J, Ferris AL, Mellors JW, Kearney MF, Coffin JM, Hughes SH.
Specific HIV integration sites are linked to clonal expansion and persistence of infected cells.
Science. 2014.
Full Text Article. In Press. [Journal]
2)  Kearney MF, Spindler J, Shao W, Yu S, Anderson EM, O'Shea A, Rehm C, Poethke C, Kovacs N, Mellors JW, Coffin JM, Maldarelli F.
Lack of Detectable HIV-1 Molecular Evolution during Suppressive Antiretroviral Therapy.
PLoS Pathog. 10: e1004010, 2014.
[Journal]
3)  Kearney M, Spindler J, Wiegand A, Shao W, Anderson E, Maldarelli F, Ruscetti F, Mellors J, Hughes S, Le Grice S, Coffin J.
Multiple sources of contamination in samples from patients reported to have XMRV infection.
PLoS ONE. 7(2): e30889, 2012.
Full Text Article. [Journal]
4)  Kearney M, Spindler J, Shao W, Maldarelli F, Palmer S, Hu SL, Lifson JD, Kewalramani VN, Mellors JW, Coffin JM, Ambrose Z.
Genetic Diversity of Simian Immunodeficiency Virus Encoding HIV-1 Reverse Transcriptase Persists in Macaques despite Antiretroviral Therapy.
J. Virol. 85: 1067-76, 2011.
[Journal]
5)  Kearney M, Maldarelli F, Shao W, Margolick JB, Daar ES, Mellors JW, Rao V, Coffin JM, Palmer S.
Human immunodeficiency virus type 1 population genetics and adaptation in newly infected individuals.
J. Virol. 83: 2715-27, 2009.
[Journal]
6)  Wei D, Chiang V, Fyne E, Balakrishnan M, Barnes T, Graupe M, Hesselgesser J, Irrinki I, Murry J, Stepan G, Stray K, Tsai A, Yu H, Spindler J, Kearney M, Spina C, McMahon D, Lalezari J, Sloan D, Mellors J, Geleziunas R, Cihlar T.
Histone deacetylase inhibitor romidepsin induces HIV expression in CD4 T cells from patients on suppressive antiretroviral therapy at concentrations achieved by clinical dosing.
PLoS Pathog. 10(4): e1004071, 2014.
Full Text Article. [Journal]
7)  Shao W, Kearney MF, Boltz VF, Spindler JE, Mellors JW, Maldarelli F, Coffin JM.
PAPNC, a novel method to calculate nucleotide diversity from large scale next generation sequencing data.
J. Virol. Methods. 203C: 73-80, 2014.
[Journal]
8)  De Ravin SS, Gray JT, Throm RE, Spindler J, Kearney M, Wu X, Coffin JM, Hughes SH, Malderelli F, Sorrentino BP, Malech HL.
False-Positive HIV PCR Test Following Ex Vivo Lentiviral Gene Transfer Treatment of X-linked Severe Combined Immunodeficiency Vector.
Mol. Ther. 22: 244-5, 2014.
[Journal]
9)  Archin NM, Bateson R, Tripathy M, Crooks AM, Yang KH, Dahl NP, Kearney MF, Anderson EM, Coffin JM, Strain MC, Richman DD, Robertson KR, Kashuba AD, Bosch RJ, Hazuda DJ, Kuruc JD, Eron JJ, Margolis DM.
HIV-1 Expression within Resting CD4 T-Cells Following Multiple Doses of Vorinostat.
J. Infect. Dis. 2014.
[Journal]
10)  Boltz VF, Bao Y, Lockman S, Halvas EK, Kearney MF, McIntyre JA, Schooley RT, Hughes MD, Coffin JM, Mellors JW.
Low-Frequency Nevirapine (NVP)-Resistant HIV-1 Variants Are Not Associated With Failure of Antiretroviral Therapy in Women Without Prior Exposure to Single-Dose NVP.
J. Infect. Dis. 209: 703-10, 2014.
[Journal]
Click Here to View Expanded Bibliography.

This page was last updated on 6/28/2014.