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Our Science – Nelson Website

George W. Nelson, Ph.D.

Selected Publications

1)  Lipkowitz MS, Freedman BI, Langefeld CD, Comeau ME, Bowden DW, Kao WH, Astor BC, Bottinger EP, Iyengar SK, Klotman PE, Freedman RG, Zhang W, Parekh RS, Choi MJ, Nelson GW, Winkler CA, Kopp JB.
Apolipoprotein L1 gene variants associate with hypertension-attributed nephropathy and the rate of kidney function decline in African Americans.
Kidney Int. 83: 114-20, 2013.
2)  Schwarz J, Astermark J, Menius ED, Carrington M, Donfield SM, Gomperts ED, Nelson GW, Oldenburg J, Pavlova A, Shapiro AD, Winkler CA, Berntorp E.
F8 haplotype and inhibitor risk: results from the Hemophilia Inhibitor Genetics Study (HIGS) Combined Cohort.
Haemophilia. 19: 113-8, 2013.
3)  Atta MG, Estrella MM, Kuperman M, Foy MC, Fine DM, Racusen LC, Lucas GM, Nelson GW, Warner AC, Winkler CA, Kopp JB.
HIV-associated nephropathy patients with and without apolipoprotein L1 gene variants have similar clinical and pathological characteristics.
Kidney Int. 82: 338-43, 2012.
4)  Kopp JB, Nelson GW, Sampath K, Johnson RC, Genovese G, An P, Friedman D, Briggs W, Dart R, Korbet S, Mokrzycki MH, Kimmel PL, Limou S, Ahuja TS, Berns JS, Fryc J, Simon EE, Smith MC, Trachtman H, Michel DM, Schelling JR, Vlahov D, Pollak M, Winkler CA.
APOL1 genetic variants in focal segmental glomerulosclerosis and HIV-associated nephropathy.
J. Am. Soc. Nephrol. 22: 2129-37, 2011.
5)  Freedman BI, Langefeld CD, Lu L, Divers J, Comeau ME, Kopp JB, Winkler CA, Nelson GW, Johnson RC, Palmer ND, Hicks PJ, Bostrom MA, Cooke JN, McDonough CW, Bowden DW.
Differential effects of MYH9 and APOL1 risk variants on FRMD3 Association with Diabetic ESRD in African Americans.
PLoS Genet. 7: e1002150, 2011.
6)  Troyer JL, Nelson GW, Lautenberger JA, Chinn L, McIntosh C, Johnson RC, Sezgin E, Kessing B, Malasky M, Hendrickson SL, Li G, Pontius J, Tang M, An P, Winkler CA, Limou S, Le Clerc S, Delaneau O, Zagury JF, Schuitemaker H, van Manen D, Bream JH, Gomperts ED, Buchbinder S, Goedert JJ, Kirk GD, O'Brien SJ.
Genome-wide association study implicates PARD3B-based AIDS restriction.
J. Infect. Dis. 203: 1491-502, 2011.
7)  An P, Li R, Wang JM, Yoshimura T, Takahashi M, Samudralal R, O'Brien SJ, Phair J, Goedert JJ, Kirk GD, Troyer JL, Sezgin E, Buchbinder SP, Donfield S, Nelson GW, Winkler CA.
Role of exonic variation in chemokine receptor genes on AIDS: CCRL2 F167Y association with pneumocystis pneumonia.
PLoS Genet. 7: e1002328, 2011.
8)  Johnson RC, Nelson GW, Troyer JL, Lautenberger JA, Kessing BD, Winkler CA, O'Brien SJ.
Accounting for multiple comparisons in a genome-wide association study (GWAS).
BMC Genomics. 11: 724, 2010.
9)  Winkler CA, Nelson GW, Smith MW.
Admixture mapping comes of age.
Annu Rev Genomics Hum Genet. 11: 65-89, 2010.
10)  Behar DM, Rosset S, Tzur S, Selig S, Yudkovsky G, Bercovici S, Kopp JB, Winkler CA, Nelson GW, Wasser WG, Skorecki K.
African ancestry allelic variation at the MYH9 gene contributes to increased susceptibility to non-diabetic end-stage kidney disease in Hispanic Americans.
Hum. Mol. Genet. 19: 1816-27, 2010.
11)  Genovese G, Friedman DJ, Ross MD, Lecordier L, Uzureau P, Freedman BI, Bowden DW, Langefeld CD, Oleksyk TK, Uscinski Knob AL, Bernhardy AJ, Hicks PJ, Nelson GW, Vanhollebeke B, Winkler CA, Kopp JB, Pays E, Pollak MR.
Association of trypanolytic ApoL1 variants with kidney disease in African Americans.
Science. 329: 841-5, 2010.
12)  Nelson GW, Freedman BI, Bowden DW, Langefeld CD, An P, Hicks PJ, Bostrom MA, Johnson RC, Kopp JB, Winkler CA.
Dense mapping of MYH9 localizes the strongest kidney disease associations to the region of introns 13 to 15.
Hum. Mol. Genet. 19: 1805-15, 2010.
13)  Herbeck JT, Gottlieb GS, Winkler CA, Nelson GW, An P, Maust BS, Wong KG, Troyer JL, Goedert JJ, Kessing BD, Detels R, Wolinsky SM, Martinson J, Buchbinder S, Kirk GD, Jacobson LP, Margolick JB, Kaslow RA, O'Brien SJ, Mullins JI.
Multistage genomewide association study identifies a locus at 1q41 associated with rate of HIV-1 disease progression to clinical AIDS.
J. Infect. Dis. 201: 618-26, 2010.
14)  Kopp JB, Winkler CA, Nelson GW.
MYH9 genetic variants associated with glomerular disease: what is the role for genetic testing?.
Semin. Nephrol. 30: 409-17, 2010.
15)  Freedman BI, Kopp JB, Langefeld CD, Genovese G, Friedman DJ, Nelson GW, Winkler CA, Bowden DW, Pollak MR.
The apolipoprotein L1 (APOL1) gene and nondiabetic nephropathy in African Americans.
J. Am. Soc. Nephrol. 21: 1422-6, 2010.
16)  Freedman BI, Edberg JC, Comeau ME, Murea M, Bowden DW, Divers J, Alarcón GS, Brown EE, McGwin G, Kopp JB, Winkler CA, Nelson GW, Illei G, Petri M, Ramsey-Goldman R, Reveille JD, Vilá LM, Langefeld CD, Kimberly RP.
The non-muscle Myosin heavy chain 9 gene (MYH9) is not associated with lupus nephritis in African Americans.
Am. J. Nephrol. 32: 66-72, 2010.
17)  Oleksyk TK, Nelson GW, An P, Kopp JB, Winkler CA.
Worldwide distribution of the MYH9 kidney disease susceptibility alleles and haplotypes: evidence of historical selection in Africa.
PLoS ONE. 5: e11474, 2010.
18)  Guo X, Johnson RC, Deng H, Liao J, Guan L, Nelson GW, Tang M, Zheng Y, de The G, O'Brien SJ, Winkler CA, Zeng Y.
Evaluation of nonviral risk factors for nasopharyngeal carcinoma in a high-risk population of Southern China.
Int. J. Cancer. 124: 2942-7, 2009.
19)  Winkler CA, An P, Johnson R, Nelson GW, Kirk G.
Expression of Duffy antigen receptor for chemokines (DARC) has no effect on HIV-1 acquisition or progression to AIDS in African Americans.
Cell Host Microbe. 5: 411-3; author reply 418-9, 2009.
20)  Julg B, Reddy S, van der Stok M, Kulkarni S, Qi Y, Bass S, Gold B, Nalls MA, Nelson GW, Walker BD, Carrington M, Ndung'u T.
Lack of Duffy antigen receptor for chemokines: no influence on HIV disease progression in an African treatment-naive population.
Cell Host Microbe. 5: 413-5; author reply 418-9, 2009.
21)  Freedman BI, Hicks PJ, Bostrom MA, Comeau ME, Divers J, Bleyer AJ, Kopp JB, Winkler CA, Nelson GW, Langefeld CD, Bowden DW.
Non-muscle myosin heavy chain 9 gene MYH9 associations in African Americans with clinically diagnosed type 2 diabetes mellitus-associated ESRD.
Nephrol. Dial. Transplant. 24: 3366-71, 2009.
22)  Freedman BI, Hicks PJ, Bostrom MA, Cunningham ME, Liu Y, Divers J, Kopp JB, Winkler CA, Nelson GW, Langefeld CD, Bowden DW.
Polymorphisms in the non-muscle myosin heavy chain 9 gene (MYH9) are strongly associated with end-stage renal disease historically attributed to hypertension in African Americans.
Kidney Int. 75: 736-45, 2009.
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This page was last updated on 4/10/2014.