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Our Science – Grewal Website

Shiv Grewal, Ph.D.

Selected Publications

1)  Lee NN, Chalamcharla VR, Reyes-Turcu F, Mehta S, Zofall M, Balachandran V, Dhakshnamoorthy J, Taneja N, Yamanaka S, Zhou M, Grewal SI.
Mtr4-like Protein Coordinates Nuclear RNA Processing for Heterochromatin Assembly and for Telomere Maintenance.
Cell. 155: 1061-74, 2013.
2)  Yamanaka S, Mehta S, Reyes-Turcu FE, Zhuang F, Fuchs RT, Rong Y, Robb GB, Grewal SI.
RNAi triggered by specialized machinery silences developmental genes and retrotransposons.
Nature. 493: 557-60, 2013.
3)  Aygün O, Mehta S, Grewal SI.
HDAC-mediated suppression of histone turnover promotes epigenetic stability of heterochromatin.
Nat. Struct. Mol. Biol. 20: 547-54, 2013.
4)  Zofall M, Yamanaka S, Reyes-Turcu FE, Zhang K, Rubin C, Grewal SI.
RNA elimination machinery targeting meiotic mRNAs promotes facultative heterochromatin formation.
Science. 335: 96-100, 2012.
5)  Zhang K, Fischer T, Porter RL, Dhakshnamoorthy J, Zofall M, Zhou M, Veenstra T, Grewal SI.
Clr4/Suv39 and RNA quality control factors cooperate to trigger RNAi and suppress antisense RNA.
Science. 331: 1624-7, 2011.
6)  Matsuda E, Sugioka-Sugiyama R, Mizuguchi T, Mehta S, Cui B, Grewal SI.
A homolog of male sex-determining factor SRY cooperates with a transposon-derived CENP-B protein to control sex-specific directed recombination.
Proc. Natl. Acad. Sci. U.S.A. 108: 18754-9, 2011.
7)  Yamane K, Mizuguchi T, Cui B, Zofall M, Noma K, Grewal SI.
Asf1/HIRA Facilitate Global Histone Deacetylation and Associate with HP1 to Promote Nucleosome Occupancy at Heterochromatic Loci.
Mol. Cell. 41: 56-66, 2011.
8)  Grewal SI, Jia S.
Heterochromatin revisited.
Nat. Rev. Genet. 8: 35-46, 2007.
9)  Reyes-Turcu FE, Zhang K, Zofall M, Chen E, Grewal SI.
Defects in RNA quality control factors reveal RNAi-independent nucleation of heterochromatin.
Nature Struct Mol Biol. 18:: 1132-8, 2011.
10)  Reyes-Turcu FE, Grewal SI.
Different means, same end-heterochromatin formation by RNAi and RNAi-independent RNA processing factors in fission yeast.
Curr. Opin. Genet. Dev. 22: 156-63, 2012.
Click Here to View Expanded Bibliography.

This page was last updated on 11/27/2013.