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Our Science – Onda Website

Masanori Onda, M.D., Ph.D.

Selected Publications

1)  Pastan I, Onda M, Weldon J, FitzGerald D, Kreitman R.
Immunotoxins with decreased immunogenicity and improved activity.
Leukemia and lymphoma. 52 (S2): 87-90, 2011.
[Journal]
2)  Onda M, Mossoba M, Taylor J, Massey P, Treadwell S, Sharon E, Hassan R, Pastan I, Fowler D.
Pentostatin plus cyclophosphamide safely and effectively prevents immunotoxin immunogenicity in murine hosts.
Clin Cancer Res. 17: In Press, 2011.
[Journal]
3)  Onda M, Beers R, Xiang L, Lee B, Weldon J, Kreitman R, Pastan I.
Recombinant immunotoxin against B-cell malignancies with no immunogenicity in mice by removal of B-cell epitopes.
Proc. Natl. Acad. Sci. USA. 108: 5742-57457, 2011.
[Journal]
4)  Zhang Y, Hansen J, Xiang L, Kawa S, Onda M, Ho M, Hassan R, Pastan I.
A flow cytometry method to quantitate internalized immunotoxin shows that Taxol synergistically increase cellular immunotoxins uptake.
Cancer Res. 70: 1082-1089, 2010.
[Journal]
5)  Hansen J, Weldon J, Xiang L, Beers R, Onda M, Pastan I.
A recombinant immunotoxin targeting CD22 with low immunogenicity, low nonspecific toxicity and high anti-tumor activity in mice.
J. Immunother. 33: 297-304, 2010.
[Journal]
6)  Onda M.
Reducing the immunogenicity of protein therapeutics.
Curr. Drug Targets. 10: 131-139, 2009.
[Journal]
7)  Matsushita K, Margulies I, Onda M, Nagata S, Stetler-Stevenson M, Kreitman R.
Soluble CD22 as a tumor marker for hairy cell leukemia.
Blood. 112: 2272-2277, 2008.
[Journal]
8)  Kobayashi T, Kai N, Kobayashi K, Fujiwara T, Akagawa K, Onda M, Kobayasi K.
Transient silencing of synaptic transmitter release from specific neuronal types by recombinant tetanus toxin light chain fused to antibody variable region.
J. Neurosci. Methods. 175: 125-132, 2008.
[Journal]
9)  Onda M, Beers R, Xiang L, Nagata S, Wang Q, Pastan I.
An Immunotoxin with greatly reduced immunogenicity by identification and removal of B cell epitopes.
Proc. Natl. Acad. Sci. USA. 105: 11311-11316, 2008.
[Journal]
10)  Ise T, Das S, Nagata S, Maeda H, Lee Y, Onda M, Anver MR, Bera TK, Pastan I.
Expression of POTE protein in human testis detected by novel monoclonal antibodies.
Biochem Biophys Res Commun. 2007.
[Journal]
Click Here to View Expanded Bibliography.

This page was last updated on 5/31/2011.