Our Science – Trepel Website
Jane B. Trepel
Selected Publications |
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| 1)
Park SR, Speranza G, Piekarz R, Wright JJ, Kinders RJ, Wang L, Pfister T, Trepel JB, Lee MJ, Alarcon S, Steinberg SM, Collins J, Doroshow JH, Kummar S. A multi-histology trial of fostamatinib in patients with advanced colorectal, non-small cell lung, head and neck, thyroid, and renal cell carcinomas, and pheochromocytomas. Cancer Chemother. Pharmacol. 71: 981-90, 2013. [Journal] |
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| 2)
Bellon M, Ko NL, Lee M, Yao Y, Waldmann TA, Trepel JB, Nicot C. Adult T-cell leukemia cells over-express Wnt5a and promote osteoclast differentiation. Blood. [Epub ahead of print], 2013. [Journal] |
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| 3)
Sourbier C, Scroggins BT, Ratnayake R, Prince TL, Lee S, Lee MJ, Nagy PL, Lee YH, Trepel JB, Beutler JA, Linehan WM, Neckers L. Englerin A stimulates PKC? to inhibit insulin signaling and to simultaneously activate HSF1: pharmacologically induced synthetic lethality. Cancer Cell. 23: 228-37, 2013. [Journal] |
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| 4)
Yardley DA, Ismail-Khan RR, Melichar B, Lichinitser M, Munster PN, Klein PM, Cruickshank S, Miller KD, Lee MJ, Trepel JB. Randomized Phase II, Double-Blind, Placebo-Controlled Study of Exemestane With or Without Entinostat in Postmenopausal Women With Locally Recurrent or Metastatic Estrogen Receptor-Positive Breast Cancer Progressing on Treatment With a Nonsteroidal Aromatase Inhibitor. J. Clin. Oncol. [Epub ahead of print], 2013. [Journal] |
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| 5)
Giubellino A, Sourbier C, Lee MJ, Scroggins B, Bullova P, Landau M, Ying W, Neckers L, Trepel JB, Pacak K. Targeting heat shock protein 90 for the treatment of malignant pheochromocytoma. PLoS ONE. 8: e56083, 2013. [Journal] |
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| 6)
Iwai A, Bourboulia D, Mollapour M, Jensen-Taubman S, Lee S, Donnelly AC, Yoshida S, Miyajima N, Tsutsumi S, Smith AK, Sun D, Wu X, Blagg BS, Trepel JB, Stetler-Stevenson WG, Neckers L. Combined inhibition of Wee1 and Hsp90 activates intrinsic apoptosis in cancer cells. Cell Cycle. 11: 3649-55, 2012. [Journal] |
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| 7)
Xu W, Mollapour M, Prodromou C, Wang S, Scroggins BT, Palchick Z, Beebe K, Siderius M, Lee M, Couvillon A, Trepel JB, Miyata Y, Matts R, Neckers L. Dynamic Tyrosine Phosphorylation Modulates Cycling of the HSP90-P50(CDC37)-AHA1 Chaperone Machine. Mol Cell. 47: 434-43, 2012. [Journal] |
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| 8)
Solier S, Kohn KW, Scroggins B, Xu W, Trepel J, Neckers L, Pommier Y. Feature Article: Heat shock protein 90alpha (HSP90alpha), a substrate and chaperone of DNA-PK necessary for the apoptotic response. Proc Natl Acad Sci U S A. 109: 12866-72, 2012. [Journal] |
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| 9)
Kim YS, Kumar V, Lee S, Iwai A, Neckers L, Malhotra SV, Trepel JB. Methoxychalcone inhibitors of androgen receptor translocation and function. Bioorg. Med. Chem. Lett. 22: 2105-9, 2012. [Journal] |
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| 10)
Alarcon SV, Mollapour M, Lee M-, Tsutsumi S, Lee S, Kim YS, Prince T, Apolo A, Giaccone G, Xu W, Neckers LM, Trepel JB. Tumor-Intrinsic and Tumor-Extrinsic Factors Impacting Hsp90-Targeted Therapy. Curr Mol Med. 12: 1125-41, 2012. [Journal] |
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| Click Here to View Expanded Bibliography. |
This page was last updated on 5/16/2013.
