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Our Science – Ward Website

Yvona Ward, Ph.D.

Selected Publications

1)  Ward Y, Gupta S, Jensen P, Wartmann M, Davis RJ, Kelly K.
Control of MAP kinase activation by the mitogen-induced threonine/tyrosine phosphatase PAC1.
Nature. 367: 651-4, 1994.
[Journal]
2)  Ward Y, Wang W, Woodhouse E, Linnoila I, Liotta L, Kelly K.
Signal pathways which promote invasion and metastasis: critical and distinct contributions of extracellular signal-regulated kinase and Ral-specific guanine exchange factor pathways.
Mol. Cell. Biol. 21: 5958-69, 2001.
[Journal]
3)  Wang T, Ward Y, Tian L, Lake R, Guedez L, Stetler-Stevenson WG, Kelly K.
CD97, an adhesion receptor on inflammatory cells, stimulates angiogenesis through binding integrin counterreceptors on endothelial cells.
Blood. 105: 2836-44, 2005.
[Journal]
4)  Ward Y, Lake R, Yin JJ, Heger CD, Raffeld M, Goldsmith PK, Merino M, Kelly K.
LPA receptor heterodimerizes with CD97 to amplify LPA-initiated RHO-dependent signaling and invasion in prostate cancer cells.
Cancer Res. 71: 7301-11, 2011.
[Journal]
5)  Ward Y, Lake R, Martin PL, Killian K, Salerno P, Wang T, Meltzer P, Merino M, Cheng S, Santoro M, Garcia-Rostan G, Kelly K.
CD97 amplifies LPA receptor signaling and promotes thyroid cancer progression in a mouse model.
Oncogene. 32: 2726-38, 2013.
[Journal]
6)  Cai Z, Jitkaew S, Zhao J, Chiang HC, Choksi S, Liu J, Ward Y, Wu LG, Liu ZG.
Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis.
Nat. Cell Biol. 16: 55-65, 2014.
[Journal]
7)  Basseville A, Tamaki A, Ieranò C, Trostel S, Ward Y, Robey RW, Hegde RS, Bates SE.
Histone deacetylase inhibitors influence chemotherapy transport by modulating expression and trafficking of a common polymorphic variant of the ABCG2 efflux transporter.
Cancer Res. 72: 3642-51, 2012.
[Journal]
8)  Casey OM, Fang L, Hynes PG, Abou-Kheir WG, Martin PL, Tillman HS, Petrovics G, Awwad HO, Ward Y, Lake R, Zhang L, Kelly K.
TMPRSS2- driven ERG expression in vivo increases self-renewal and maintains expression in a castration resistant subpopulation.
PLoS ONE. 7: e41668, 2012.
[Journal]
9)  Meany HJ, Sackett DL, Maris JM, Ward Y, Krivoshik A, Cohn SL, Steinberg SM, Balis FM, Fox E.
Clinical outcome in children with recurrent neuroblastoma treated with ABT-751 and effect of ABT-751 on proliferation of neuroblastoma cell lines and on tubulin polymerization in vitro.
Pediatr Blood Cancer. 54: 47-54, 2010.
[Journal]
10)  Polgar O, Ierano C, Tamaki A, Stanley B, Ward Y, Xia D, Tarasova N, Robey RW, Bates SE.
Mutational analysis of threonine 402 adjacent to the GXXXG dimerization motif in transmembrane segment 1 of ABCG2.
Biochemistry. 49: 2235-45, 2010.
[Journal]
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This page was last updated on 7/22/2014.