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Our Science – Hussain Website

S. Perwez Hussain, Ph.D.

Selected Publications

1)  Mathé E, Nguyen GH, Funamizu N, He P, Moake M, Croce CM, Hussain SP.
Inflammation regulates microRNA expression in cooperation with p53 and nitric oxide.
Int. J. Cancer. 131: 760-5, 2012.
[Journal]
2)  Zhang G, Schetter A, He P, Funamizu N, Gaedcke J, Ghadimi BM, Ried T, Hassan R, Yfantis HG, Lee DH, Lacy C, Maitra A, Hanna N, Alexander HR, Hussain SP.
DPEP1 inhibits tumor cell invasiveness, enhances chemosensitivity and predicts clinical outcome in pancreatic ductal adenocarcinoma.
PLoS ONE. 7: e31507, 2012.
[Journal]
3)  Funamizu N, Hu C, Lacy C, Schetter A, Zhang G, He P, Gaedcke J, Ghadimi BM, Ried T, Yffantis HG, Lee DH, Subleski J, Chan T, Weiss JM, Back TC, Yanaga K, Hanna N, Alexander HR, Maitra A, Hussain SP.
Macrophage Migration Inhibitory Factor (MIF) induces epithelial to mesenchymal transition, enhances tumor aggressiveness and predicts clinical outcome in resected pancreatic ductal adenocarcinoma.
Int J Cancer. 132: 785-94, 2012.
[Journal]
4)  Zhang G, He P, Gaedcke J, Ghadimi BM, Ried T, Yfantis HG, Lee DH, Hanna N, Alexander HR, Hussain SP.
FOXL1, a Novel Candidate Tumor Suppressor, Inhibits Tumor Aggressiveness and Predicts Outcome in Human Pancreatic Cancer.
Cancer Res. 73: 5416-25, 2013.
[Journal]
5)  Zhang G, He P, Tan H, Budhu A, Gaedcke J, Ghadimi BM, Ried T, Yfantis HG, Lee DH, Maitra A, Hanna N, Alexander HR, Hussain SP.
Integration of metabolomics and transcriptomics revealed a fatty acid network exerting growth inhibitory effects in human pancreatic cancer.
Clin. Cancer Res. 19: 4983-93, 2013.
[Journal]
6)  Budhu A, Terunuma A, Zhang G, Hussain S, Ambs S, Wang X.
Metabolic profiles are principally different between cancers of the liver, pancreas and breast.
Int. J. Biosciences. 2014.
In Press. [Journal]
7)  Heinecke JL, Ridnour LA, Cheng RY, Switzer CH, Lizardo MM, Khanna C, Glynn SA, Hussain SP, Young HA, Ambs S, Wink DA.
Tumor microenvironment-based feed-forward regulation of NOS2 in breast cancer progression.
Proc. Natl. Acad. Sci. U.S.A. 111: 6323-6328, 2014.
[Journal]
8)  Okayama H, Saito M, Oue N, Weiss JM, Stauffer J, Takenoshita S, Wiltrout RH, Hussain SP, Harris CC.
NOS2 enhances KRAS-induced lung carcinogenesis, inflammation and microRNA-21 expression.
Int J Cancer. 132: 9-18, 2013.
[Journal]
9)  Sohn JJ, Schetter AJ, Yfantis HG, Ridnour LA, Horikawa I, Khan MA, Robles AI, Hussain SP, Goto A, Bowman ED, Hofseth LJ, Bartkova J, Bartek J, Wogan GN, Wink DA, Harris CC.
Macrophages, nitric oxide and microRNAs are associated with DNA damage response pathway and senescence in inflammatory bowel disease.
PLoS ONE. 7: e44156, 2012.
[Journal]
10)  Weiss JM, Ridnour LA, Back T, Hussain SP, He P, Maciag AE, Keefer LK, Murphy WJ, Harris CC, Wink DA, Wiltrout RH.
Macrophage-dependent nitric oxide expression regulates tumor cell detachment and metastasis after IL-2/anti-CD40 immunotherapy.
J. Exp. Med. 207: 2455-67, 2010.
[Journal]
Click Here to View Expanded Bibliography.

This page was last updated on 7/23/2014.