Our Science – Scaffidi Website
Paola Scaffidi, Ph.D.
Selected Publications |
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| 1)
Scaffidi P, Misteli T. Lamin A-dependent misregulation of adult stem cells associated with accelerated ageing. Nat. Cell Biol. 10: 452-9, 2008. [Journal] |
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| 2)
Dahl KN, Scaffidi P, Islam MF, Yodh AG, Wilson KL, Misteli T. Distinct structural and mechanical properties of the nuclear lamina in Hutchinson-Gilford progeria syndrome. Proc. Natl. Acad. Sci. U.S.A. 103: 10271-6, 2006. [Journal] |
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| 3)
Scaffidi P, Misteli T. Good news in the nuclear envelope: loss of lamin A might be a gain. J. Clin. Invest. 116: 632-4, 2006. [Journal] |
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| 4)
Scaffidi P, Misteli T. Lamin A-dependent nuclear defects in human aging. Science. 312: 1059-63, 2006. [Journal] |
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| 5)
Misteli T, Scaffidi P. Genome instability in progeria: when repair gets old. Nat. Med. 11: 718-9, 2005. [Journal] |
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| 6)
Agresti A, Scaffidi P, Riva A, Caiolfa VR, Bianchi ME. GR and HMGB1 interact only within chromatin and influence each other's residence time. Mol. Cell. 18: 109-21, 2005. [Journal] |
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| 7)
Scaffidi P, Misteli T. Reversal of the cellular phenotype in the premature aging disease Hutchinson-Gilford progeria syndrome. Nat. Med. 11: 440-5, 2005. [Journal] |
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| 8)
Scaffidi P, Gordon L, Misteli T. The cell nucleus and aging: tantalizing clues and hopeful promises. PLoS Biol. 3: e395, 2005. [Journal] |
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| 9)
Phair RD, Scaffidi P, Elbi C, Vecerová J, Dey A, Ozato K, Brown DT, Hager G, Bustin M, Misteli T. Global nature of dynamic protein-chromatin interactions in vivo: three-dimensional genome scanning and dynamic interaction networks of chromatin proteins. Mol. Cell. Biol. 24: 6393-402, 2004. [Journal] |
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| 10)
Rovere-Querini P, Capobianco A, Scaffidi P, Valentinis B, Catalanotti F, Giazzon M, Dumitriu IE, Müller S, Iannacone M, Traversari C, Bianchi ME, Manfredi AA. HMGB1 is an endogenous immune adjuvant released by necrotic cells. EMBO Rep. 5: 825-30, 2004. [Journal] |
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| 11)
Pallier C, Scaffidi P, Chopineau-Proust S, Agresti A, Nordmann P, Bianchi ME, Marechal V. Association of chromatin proteins high mobility group box (HMGB) 1 and HMGB2 with mitotic chromosomes. Mol. Biol. Cell. 14: 3414-26, 2003. [Journal] |
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| 12)
Bonaldi T, Talamo F, Scaffidi P, Ferrera D, Porto A, Bachi A, Rubartelli A, Agresti A, Bianchi ME. Monocytic cells hyperacetylate chromatin protein HMGB1 to redirect it towards secretion. EMBO J. 22: 5551-60, 2003. [Journal] |
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| 13)
Scaffidi P, Misteli T, Bianchi ME. Release of chromatin protein HMGB1 by necrotic cells triggers inflammation. Nature. 418: 191-5, 2002. [Journal] |
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| 14)
Müller S, Scaffidi P, Degryse B, Bonaldi T, Ronfani L, Agresti A, Beltrame M, Bianchi ME. New EMBO members' review: the double life of HMGB1 chromatin protein: architectural factor and extracellular signal. EMBO J. 20: 4337-40, 2001. [Journal] |
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| 15)
Scaffidi P, Bianchi ME. Spatially precise DNA bending is an essential activity of the sox2 transcription factor. J. Biol. Chem. 276: 47296-302, 2001. [Journal] |
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This page was last updated on 9/30/2008.
