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Our Science – Hathcock Website

Karen S. Hathcock, B.S.

Selected Publications

1)  Hathcock KS, Bowen S, Livak F, Hodes RJ.
ATM influences the efficiency of TCRß rearrangement, subsequent TCRß-dependent T cell development, and generation of the pre-selection TCRß CDR3 repertoire.
PLoS ONE. 8: e62188, 2013.
2)  Padilla-Nash HM, Hathcock K, McNeil NE, Mack D, Hoeppner D, Ravin R, Knutsen T, Yonescu R, Wangsa D, Dorritie K, Barenboim L, Hu Y, Ried T.
Spontaneous transformation of murine epithelial cells requires the early acquisition of specific chromosomal aneuploidies and genomic imbalances.
Genes Chromosomes Cancer. 51: 353-74, 2012.
3)  Gegonne A, Tai X, Zhang J, Wu G, Zhu J, Yoshimoto A, Hanson J, Cultraro C, Chen QR, Guinter T, Yang Z, Hathcock K, Singer A, Rodriguez-Canales J, Tessarollo L, Mackem S, Meerzaman D, Buetow K, Singer DS.
The general transcription factor TAF7 is essential for embryonic development but not essential for the survival or differentiation of mature T cells.
Mol. Cell. Biol. 32: 1984-97, 2012.
4)  Hathcock KS, Farrington L, Ivanova I, Livak F, Selimyan R, Sen R, Williams J, Tai X, Hodes RJ.
The requirement for pre-TCR during thymic differentiation enforces a developmental pause that is essential for V-DJß rearrangement.
PLoS ONE. 6: e20639, 2011.
5)  Chiang YJ, Calado RT, Hathcock KS, Lansdorp PM, Young NS, Hodes RJ.
Telomere length is inherited with resetting of the telomere set-point.
Proc. Natl. Acad. Sci. U.S.A. 107: 10148-53, 2010.
Click Here to View Expanded Bibliography.

This page was last updated on 4/10/2014.