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Our Science – Chiang Website

Yungping (Jeffrey) Chiang, Ph.D.

Selected Publications

1)  Zuo W, Huang F, Chiang YJ, Li M, Du J, Ding Y, Zhang T, Lee HW, Jeong LS, Chen Y, Deng H, Feng XH, Luo S, Gao C, Chen YG.
c-Cbl-mediated neddylation antagonizes ubiquitination and degradation of the TGF-ß type II receptor.
Mol. Cell. 49: 499-510, 2013.
2)  Lu J, Frerich JM, Turtzo LC, Li S, Chiang J, Yang C, Wang X, Zhang C, Wu C, Sun Z, Niu G, Zhuang Z, Brady RO, Chen X.
Histone deacetylase inhibitors are neuroprotective and preserve NGF-mediated cell survival following traumatic brain injury.
Proc. Natl. Acad. Sci. U.S.A. 110: 10747-52, 2013.
3)  Chiang YJ, Difilippantonio MJ, Tessarollo L, Morse HC, Hodes RJ.
Exon 1 disruption alters tissue-specific expression of mouse p53 and results in selective development of B cell lymphomas.
PLoS ONE. 7: e49305, 2012.
4)  Chiang J, Hodes RJ.
Cbl enforces Vav1 dependence and a restricted pathway of T cell development.
PLoS ONE. 6: e18542, 2011.
5)  Martiniova L, Lu J, Chiang J, Bernardo M, Lonser R, Zhuang Z, Pacak K.
Pharmacologic modulation of serine/threonine phosphorylation highly sensitizes PHEO in a MPC cell and mouse model to conventional chemotherapy.
PLoS ONE. 6: e14678, 2011.
6)  Lu J, Chiang J, Iyer RR, Thompson E, Kaneski CR, Xu DS, Yang C, Chen M, Hodes RJ, Lonser RR, Brady RO, Zhuang Z.
Decreased glucocerebrosidase activity in Gaucher disease parallels quantitative enzyme loss due to abnormal interaction with TCP1 and c-Cbl.
Proc. Natl. Acad. Sci. U.S.A. 2010.
7)  Jang IK, Zhang J, Chiang YJ, Kole HK, Cronshaw DG, Zou Y, Gu H.
Grb2 functions at the top of the T-cell antigen receptor-induced tyrosine kinase cascade to control thymic selection.
Proc. Natl. Acad. Sci. U.S.A. 107: 10620-5, 2010.
8)  Wen J, Chiang YJ, Gao C, Xue H, Xu J, Ning Y, Hodes RJ, Gao X, Chen YG.
Loss of Dact1 disrupts planar cell polarity signaling by altering dishevelled activity and leads to posterior malformation in mice.
J. Biol. Chem. 285: 11023-30, 2010.
9)  Chiang YJ, Calado RT, Hathcock KS, Lansdorp PM, Young NS, Hodes RJ.
Telomere length is inherited with resetting of the telomere set-point.
Proc. Natl. Acad. Sci. U.S.A. 107: 10148-53, 2010.
10)  Chiang YJ, Jordan MS, Horai R, Schwartzberg PL, Koretzky GA, Hodes RJ.
Cbl enforces an SLP76-dependent signaling pathway for T cell differentiation.
J. Biol. Chem. 284: 4429-38, 2009.
Click Here to View Expanded Bibliography.

This page was last updated on 10/30/2013.