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Xuguang Tai, Ph.D.
Van Laethem F, Sarafova SD, Park JH, Tai X, Pobezinsky L, Guinter TI, Adoro S, Adams A, Sharrow SO, Feigenbaum L, Singer A.
Deletion of CD4 and CD8 coreceptors permits generation of alphabetaT cells that recognize antigens independently of the MHC.
Immunity. 27: 735-50, 2007. [Journal]
Tai X, Van Laethem F, Sharpe AH, Singer A.
Induction of autoimmune disease in CTLA-4 / mice depends on a specific CD28 motif that is required for in vivo costimulation.
Proc. Natl. Acad. Sci. U.S.A. 104: 13756-61, 2007. [Journal]
Graham DB, Bell MP, Huntoon CJ, Griffin MD, Tai X, Singer A, McKean DJ.
CD28 ligation costimulates cell death but not maturation of double-positive thymocytes due to defective ERK MAPK signaling.
J. Immunol. 177: 6098-107, 2006. [Journal]
Tai X, Cowan M, Feigenbaum L, Singer A.
CD28 costimulation of developing thymocytes induces Foxp3 expression and regulatory T cell differentiation independently of interleukin 2.
Nat. Immunol. 6: 152-62, 2005. [Journal]
Bhandoola A, Tai X, Eckhaus M, Auchincloss H, Mason K, Rubin SA, Carbone KM, Grossman Z, Rosenberg AS, Singer A.
Peripheral expression of self-MHC-II influences the reactivity and self-tolerance of mature CD4(+) T cells: evidence from a lymphopenic T cell model.
Immunity. 17: 425-36, 2002. [Journal]
McKean DJ, Huntoon CJ, Bell MP, Tai X, Sharrow S, Hedin KE, Conley A, Singer A.
Maturation versus death of developing double-positive thymocytes reflects competing effects on Bcl-2 expression and can be regulated by the intensity of CD28 costimulation.
J. Immunol. 166: 3468-75, 2001. [Journal]
Chen HT, Bhandoola A, Difilippantonio MJ, Zhu J, Brown MJ, Tai X, Rogakou EP, Brotz TM, Bonner WM, Ried T, Nussenzweig A.
Response to RAG-mediated VDJ cleavage by NBS1 and gamma-H2AX.
Science. 290: 1962-5, 2000. [Journal]
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This page was last updated on 1/31/2008.