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Our Science – Kruhlak Website

Michael J. Kruhlak, Ph.D.

Selected Publications

1)  Nguyen VP, Chen J, Petrus MN, Goldman CK, Kruhlak MJ, Bamford RN, Waldmann TA.
A new domain in the Toll/IL-1R domain-containing adaptor inducing interferon-ß factor protein amino terminus is important for tumor necrosis factor-a receptor-associated factor 3 association, protein stabilization and interferon signaling.
J Innate Immun. 6: 377-93, 2014.
2)  Wang P, Zhou Z, Hu A, Ponte de Albuquerque C, Zhou Y, Hong L, Sierecki E, Ajiro M, Kruhlak M, Harris C, Guan KL, Zheng ZM, Newton AC, Sun P, Zhou H, Fu XD.
Both decreased and increased SRPK1 levels promote cancer by interfering with PHLPP-mediated dephosphorylation of Akt.
Mol. Cell. 54: 378-91, 2014.
3)  Polato F, Callen E, Wong N, Faryabi R, Bunting S, Chen HT, Kozak M, Kruhlak MJ, Reczek CR, Lee WH, Ludwig T, Baer R, Feigenbaum L, Jackson S, Nussenzweig A.
CtIP-mediated resection is essential for viability and can operate independently of BRCA1.
J. Exp. Med. 211: 1027-36, 2014.
4)  Yang Y, Schmitz R, Mitala J, Whiting A, Xiao W, Ceribelli M, Wright GW, Zhao H, Yang Y, Xu W, Rosenwald A, Ott G, Gascoyne RD, Connors JM, Rimsza LM, Campo E, Jaffe ES, Delabie J, Smeland EB, Braziel RM, Tubbs RR, Cook JR, Weisenburger DD, Chan WC, Wiestner A, Kruhlak MJ, Iwai K, Bernal F, Staudt LM.
Essential role of the linear ubiquitin chain assembly complex in lymphoma revealed by rare germline polymorphisms.
Cancer Discov. 4: 480-93, 2014.
5)  Williams JA, Zhang J, Jeon H, Nitta T, Ohigashi I, Klug D, Kruhlak MJ, Choudhury B, Sharrow SO, Granger L, Adams A, Eckhaus MA, Jenkinson SR, Richie ER, Gress RE, Takahama Y, Hodes RJ.
Thymic medullary epithelium and thymocyte self-tolerance require cooperation between CD28-CD80/86 and CD40-CD40L costimulatory pathways.
J. Immunol. 192: 630-40, 2014.
6)  Callen E, Di Virgilio M, Kruhlak MJ, Nieto-Soler M, Wong N, Chen HT, Faryabi RB, Polato F, Santos M, Starnes LM, Wesemann DR, Lee JE, Tubbs A, Sleckman BP, Daniel JA, Ge K, Alt FW, Fernandez-Capetillo O, Nussenzweig MC, Nussenzweig A.
53BP1 Mediates Productive and Mutagenic DNA Repair through Distinct Phosphoprotein Interactions.
Cell. 153: 1266-80, 2013.
7)  Lamy L, Ngo VN, Emre NC, Shaffer AL, Yang Y, Tian E, Nair V, Kruhlak MJ, Zingone A, Landgren O, Staudt LM.
Control of autophagic cell death by caspase-10 in multiple myeloma.
Cancer Cell. 23: 435-49, 2013.
8)  Kruhlak MJ.
Correlative fluorescence and EFTEM imaging of the organized components of the mammalian nucleus.
Methods Mol. Biol. 950: 397-416, 2013.
9)  Massimelli MJ, Majerciak V, Kruhlak M, Zheng ZM.
Interplay between polyadenylate-binding protein 1 and Kaposi"s sarcoma-associated herpesvirus ORF57 in accumulation of polyadenylated nuclear RNA, a viral long noncoding RNA.
J. Virol. 87: 243-56, 2013.
10)  Sousa AA, Kruhlak MJ.
Introduction: nanoimaging techniques in biology.
Methods Mol. Biol. 950: 1-10, 2013.
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This page was last updated on 8/4/2014.