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Our Science – Kruhlak Website

Michael J. Kruhlak, Ph.D.

Selected Publications

1)  Callen E, Di Virgilio M, Kruhlak MJ, Nieto-Soler M, Wong N, Chen HT, Faryabi RB, Polato F, Santos M, Starnes LM, Wesemann DR, Lee JE, Tubbs A, Sleckman BP, Daniel JA, Ge K, Alt FW, Fernandez-Capetillo O, Nussenzweig MC, Nussenzweig A.
53BP1 Mediates Productive and Mutagenic DNA Repair through Distinct Phosphoprotein Interactions.
Cell. 153: 1266-80, 2013.
[Journal]
2)  Massimelli MJ, Majerciak V, Kruhlak M, Zheng ZM.
Interplay between polyadenylate-binding protein 1 and Kaposi"s sarcoma-associated herpesvirus ORF57 in accumulation of polyadenylated nuclear RNA, a viral long noncoding RNA.
J. Virol. 87: 243-56, 2013.
[Journal]
3)  Lamy L, Ngo VN, Emre NC, Shaffer AL, Yang Y, Tian E, Nair V, Kruhlak MJ, Zingone A, Landgren O, Staudt LM.
Control of autophagic cell death by caspase-10 in multiple myeloma.
Cancer Cell. 23: 435-49, 2013.
[Journal]
4)  Kruhlak MJ.
Correlative fluorescence and EFTEM imaging of the organized components of the mammalian nucleus.
Methods Mol. Biol. 950: 397-416, 2013.
[Journal]
5)  Sousa AA, Kruhlak MJ.
Introduction: nanoimaging techniques in biology.
Methods Mol. Biol. 950: 1-10, 2013.
[Journal]
6)  Ben-Aissa K, Patino-Lopez G, Belkina NV, Maniti O, Rosales T, Hao JJ, Kruhlak MJ, Knutson JR, Picart C, Shaw S.
Activation of Moesin, a Protein That Links Actin Cytoskeleton to the Plasma Membrane, Occurs by Phosphatidylinositol 4,5-bisphosphate (PIP2) Binding Sequentially to Two Sites and Releasing an Autoinhibitory Linker.
J. Biol. Chem. 287: 16311-23, 2012.
[Journal]
7)  Tai X, Van Laethem F, Pobezinsky L, Guinter T, Sharrow SO, Adams A, Granger L, Kruhlak M, Lindsten T, Thompson CB, Feigenbaum L, Singer A.
Basis of CTLA-4 function in regulatory and conventional CD4+ T cells.
Blood. 119: 5155-63, 2012.
[Journal]
8)  Liu Y, Belkina NV, Park C, Nambiar R, Loughhead SM, Patino-Lopez G, Ben-Aissa K, Hao JJ, Kruhlak MJ, Qi H, von Andrian UH, Kehrl JH, Tyska MJ, Shaw S.
Constitutively active ezrin increases membrane tension, slows migration, and impedes endothelial transmigration of lymphocytes in vivo in mice.
Blood. 119: 445-53, 2012.
[Journal]
9)  Lonsdorf AS, Krämer BF, Fahrleitner M, Schönberger T, Gnerlich S, Ring S, Gehring S, Schneider SW, Kruhlak MJ, Meuth SG, Nieswandt B, Gawaz M, Enk AH, Langer HF.
Engagement of alphaIIbbeta3 (GPIIb/IIIa) with alphavbeta3 integrin mediates interaction of melanoma cells with platelets: a connection to hematogenous metastasis.
J. Biol. Chem. 287: 2168-78, 2012.
[Journal]
10)  Müller JR, Waldmann TA, Kruhlak MJ, Dubois S.
Paracrine and transpresentation functions of IL-15 are mediated by diverse splice versions of IL-15Ra in human monocytes and dendritic cells.
J. Biol. Chem. 287: 40328-38, 2012.
[Journal]
Click Here to View Expanded Bibliography.

This page was last updated on 7/5/2013.