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Our Science – Borgnia Website

Mario J. Borgnia, Ph.D.

Selected Publications

1)  Milne JL, Wu X, Borgnia MJ, Lengyel JS, Brooks BR, Shi D, Perham RN, Subramaniam S.
Molecular structure of a 9-MDa icosahedral pyruvate dehydrogenase subcomplex containing the E2 and E3 enzymes using cryoelectron microscopy.
J. Biol. Chem. 281: 4364-70, 2006.
[Journal]
2)  Borgnia MJ, Shi D, Zhang P, Milne JL.
Visualization of alpha-helical features in a density map constructed using 9 molecular images of the 1.8 MDa icosahedral core of pyruvate dehydrogenase.
J. Struct. Biol. 147: 136-45, 2004.
[Journal]
3)  Wu X, Milne JL, Borgnia MJ, Rostapshov AV, Subramaniam S, Brooks BR.
A core-weighted fitting method for docking atomic structures into low-resolution maps: application to cryo-electron microscopy.
J. Struct. Biol. 141: 63-76, 2003.
[Journal]
4)  Zhang P, Borgnia MJ, Mooney P, Shi D, Pan M, O'Herron P, Mao A, Brogan D, Milne JL, Subramaniam S.
Automated image acquisition and processing using a new generation of 4K x 4K CCD cameras for cryo electron microscopic studies of macromolecular assemblies.
J. Struct. Biol. 143: 135-44, 2003.
[Journal]
5)  Borgnia MJ, Agre P.
Reconstitution and functional comparison of purified GlpF and AqpZ, the glycerol and water channels from Escherichia coli.
Proc. Natl. Acad. Sci. U.S.A. 98: 2888-93, 2001.
[Journal]
6)  Borgnia M, Nielsen S, Engel A, Agre P.
Cellular and molecular biology of the aquaporin water channels.
Annu. Rev. Biochem. 68: 425-58, 1999.
[Journal]
7)  Borgnia M, Nielsen S, Engel A, Agre P.
Cellular and molecular biology of the aquaporin water channels.
Annu. Rev. Biochem. 68: 425-58, 1999.
[Journal]
8)  Borgnia MJ, Kozono D, Calamita G, Maloney PC, Agre P.
Functional reconstitution and characterization of AqpZ, the E. coli water channel protein.
J. Mol. Biol. 291: 1169-79, 1999.
[Journal]
9)  Ringler P, Borgnia MJ, Stahlberg H, Maloney PC, Agre P, Engel A.
Structure of the water channel AqpZ from Escherichia coli revealed by electron crystallography.
J. Mol. Biol. 291: 1181-90, 1999.
[Journal]
10)  Borgnia MJ, Eytan GD, Assaraf YG.
Competition of hydrophobic peptides, cytotoxic drugs, and chemosensitizers on a common P-glycoprotein pharmacophore as revealed by its ATPase activity.
J. Biol. Chem. 271: 3163-71, 1996.
[Journal]
11)  Assaraf YG, Borgnia MJ.
Probing the interaction of the multidrug-resistance phenotype with the polypeptide ionophore gramicidin D via functional channel formation.
Eur. J. Biochem. 222: 813-24, 1994.
[Journal]
12)  Assaraf YG, Borgnia MJ.
Differential reversal of lipophilic antifolate resistance in mammalian cells with modulators of the multidrug resistance phenotype.
Anticancer Drugs. 4: 395-406, 1993.
[Journal]
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This page was last updated on 3/1/2004.