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Our Science – Borgnia Website

Mario Juan Borgnia, Ph.D.

Selected Publications

1)  Milne JL, Borgnia MJ, Bartesaghi A, Tran EE, Earl LA, Schauder DM, Lengyel J, Pierson J, Patwardhan A, Subramaniam S.
Cryo-electron microscopy--a primer for the non-microscopist.
FEBS J. 280: 28-45, 2013.
2)  Schauder DM, Kuybeda O, Zhang J, Klymko K, Bartesaghi A, Borgnia MJ, Mayer ML, Subramaniam S.
Glutamate receptor desensitization is mediated by changes in quaternary structure of the ligand binding domain.
Proc. Natl. Acad. Sci. U.S.A. 110: 5921-6, 2013.
3)  Frank GA, Bartesaghi A, Kuybeda O, Borgnia MJ, White TA, Sapiro G, Subramaniam S.
Computational separation of conformational heterogeneity using cryo-electron tomography and 3D sub-volume averaging.
J. Struct. Biol. 178: 165-76, 2012.
4)  Tran EE, Borgnia MJ, Kuybeda O, Schauder DM, Bartesaghi A, Frank GA, Sapiro G, Milne JL, Subramaniam S.
Structural mechanism of trimeric HIV-1 envelope glycoprotein activation.
PLoS Pathog. 8: e1002797, 2012.
5)  Meyerson JR, White TA, Bliss D, Moran A, Bartesaghi A, Borgnia MJ, de la Cruz MJ, Schauder D, Hartnell LM, Nandwani R, Dawood M, Kim B, Kim JH, Sununu J, Yang L, Bhatia S, Subramaniam C, Hurt DE, Gaudreault L, Subramaniam S.
Determination of molecular structures of HIV envelope glycoproteins using cryo-electron tomography and automated sub-tomogram averaging.
J Vis Exp. 2011.
6)  Khursigara CM, Lan G, Neumann S, Wu X, Ravindran S, Borgnia MJ, Sourjik V, Milne J, Tu Y, Subramaniam S.
Lateral density of receptor arrays in the membrane plane influences sensitivity of the E. coli chemotaxis response.
EMBO J. 30: 1719-29, 2011.
7)  White TA, Bartesaghi A, Borgnia MJ, de la Cruz MJ, Nandwani R, Hoxie JA, Bess JW, Lifson JD, Milne JL, Subramaniam S.
Three-dimensional structures of soluble CD4-bound states of trimeric simian immunodeficiency virus envelope glycoproteins determined by using cryo-electron tomography.
J. Virol. 85: 12114-23, 2011.
8)  Harris A, Borgnia MJ, Shi D, Bartesaghi A, He H, Pejchal R, Kang YK, Depetris R, Marozsan AJ, Sanders RW, Klasse PJ, Milne JL, Wilson IA, Olson WC, Moore JP, Subramaniam S.
Trimeric HIV-1 glycoprotein gp140 immunogens and native HIV-1 envelope glycoproteins display the same closed and open quaternary molecular architectures.
Proc. Natl. Acad. Sci. U.S.A. 108: 11440-5, 2011.
9)  White TA, Bartesaghi A, Borgnia MJ, Meyerson JR, de la Cruz MJ, Bess JW, Nandwani R, Hoxie JA, Lifson JD, Milne JL, Subramaniam S.
Molecular architectures of trimeric SIV and HIV-1 envelope glycoproteins on intact viruses: strain-dependent variation in quaternary structure.
PLoS Pathog. 6: e1001249, 2010.
10)  Narasimha R, Aganj I, Bennett AE, Borgnia MJ, Zabransky D, Sapiro G, McLaughlin SW, Milne JL, Subramaniam S.
Evaluation of denoising algorithms for biological electron tomography.
J. Struct. Biol. 164: 7-17, 2008.
Click Here to View Expanded Bibliography.

This page was last updated on 8/30/2013.