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Our Science – Hodge Website

Deborah L. Hodge, Ph.D.

Selected Publications

1)  Hodge DL, Berthet C, Coppola V, Kastenmüller W, Buschman MD, Schaughency PM, Shirota H, Scarzello AJ, Subleski JJ, Anver MR, Ortaldo JR, Lin F, Reynolds DA, Sanford ME, Kaldis P, Tessarollo L, Klinman DM, Young HA.
IFN-gamma AU-rich element removal promotes chronic IFN-gamma expression and autoimmunity in mice.
J. Autoimmun. [Epub ahead of print], 2014.
[Journal]
2)  Hodge DL, Reynolds D, Cerbán FM, Correa SG, Baez NS, Young HA, Rodriguez-Galan MC.
MCP-1/CCR2 interactions direct migration of peripheral B and T lymphocytes to the thymus during acute infectious/inflammatory processes.
Eur. J. Immunol. 42: 2644-54, 2012.
[Journal]
3)  Subleski JJ, Hall VL, Wolfe TB, Scarzello AJ, Weiss JM, Chan T, Hodge DL, Back TC, Ortaldo JR, Wiltrout RH.
TCR-dependent and -independent activation underlie liver-specific regulation of NKT cells.
J. Immunol. 186: 838-47, 2011.
[Journal]
4)  Hodge DL, Yang J, Buschman MD, Schaughency PM, Dang H, Bere W, Yang Y, Savan R, Subleski JJ, Yin XM, Loughran TP, Young HA.
Interleukin-15 enhances proteasomal degradation of bid in normal lymphocytes: implications for large granular lymphocyte leukemias.
Cancer Res. 69: 3986-94, 2009.
[Journal]
5)  Whittaker GC, Burshtyn DN, Orr SJ, Quigley L, Hodge DL, Pascal V, Zhang W, McVicar DW.
Analysis of the linker for activation of T cells (LAT) and the linker for activation of B cells (LAB) in natural killer cells reveals a novel signaling cassette, dual usage in ITAM signaling, and influence on development of the Ly49 repertoire.
Blood. 112: 2869-77, 2008.
[Journal]
6)  Berthet C, Rodriguez-Galan MC, Hodge DL, Gooya J, Pascal V, Young HA, Keller J, Bosselut R, Kaldis P.
Hematopoiesis and thymic apoptosis are not affected by the loss of Cdk2.
Mol. Cell. Biol. 27: 5079-89, 2007.
[Journal]
7)  Ortaldo JR, Winkler-Pickett R, Wigginton J, Horner M, Bere EW, Mason AT, Bhat N, Cherry J, Sanford M, Hodge DL, Young HA.
Regulation of ITAM-positive receptors: role of IL-12 and IL-18.
Blood. 107: 1468-75, 2006.
[Journal]
8)  Hodge DL, Subleski JJ, Reynolds DA, Buschman MD, Schill WB, Burkett MW, Malyguine AM, Young HA.
The proinflammatory cytokine interleukin-18 alters multiple signaling pathways to inhibit natural killer cell death.
J. Interferon Cytokine Res. 26: 706-18, 2006.
[Journal]
9)  Bream JH, Hodge DL, Gonsky R, Spolski R, Leonard WJ, Krebs S, Targan S, Morinobu A, O'Shea JJ, Young HA.
A distal region in the interferon-gamma gene is a site of epigenetic remodeling and transcriptional regulation by interleukin-2.
J. Biol. Chem. 279: 41249-57, 2004.
[Journal]
10)  Saleh A, Davies GE, Pascal V, Wright PW, Hodge DL, Cho EH, Lockett SJ, Abshari M, Anderson SK.
Identification of probabilistic transcriptional switches in the Ly49 gene cluster: a eukaryotic mechanism for selective gene activation.
Immunity. 21: 55-66, 2004.
[Journal]
11)  Salati LM, Szeszel-Fedorowicz W, Tao H, Gibson MA, Amir-Ahmady B, Stabile LP, Hodge DL.
Nutritional regulation of mRNA processing.
J. Nutr. 134: 2437S-2443S, 2004.
[Journal]
12)  Zhang X, Rodriguez-Galán MC, Subleski JJ, Ortaldo JR, Hodge DL, Wang JM, Shimozato O, Reynolds DA, Young HA.
Peroxisome proliferator-activated receptor-gamma and its ligands attenuate biologic functions of human natural killer cells.
Blood. 104: 3276-84, 2004.
[Journal]
13)  Bodor J, Bodorova J, Bare C, Hodge DL, Young HA, Gress RE.
Differential inducibility of the transcriptional repressor ICER and its role in modulation of Fas ligand expression in T and NK lymphocytes.
Eur. J. Immunol. 32: 203-12, 2002.
[Journal]
14)  Saleh A, Makrigiannis AP, Hodge DL, Anderson SK.
Identification of a novel Ly49 promoter that is active in bone marrow and fetal thymus.
J. Immunol. 168: 5163-9, 2002.
[Journal]
15)  Hodge DL, Schill WB, Wang JM, Blanca I, Reynolds DA, Ortaldo JR, Young HA.
IL-2 and IL-12 alter NK cell responsiveness to IFN-gamma-inducible protein 10 by down-regulating CXCR3 expression.
J. Immunol. 168: 6090-8, 2002.
[Journal]
16)  Hodge DL, Martinez A, Julias JG, Taylor LS, Young HA.
Regulation of nuclear gamma interferon gene expression by interleukin 12 (IL-12) and IL-2 represents a novel form of posttranscriptional control.
Mol. Cell. Biol. 22: 1742-53, 2002.
[Journal]
17)  Ortaldo JR, Bere EW, Hodge D, Young HA.
Activating Ly-49 NK receptors: central role in cytokine and chemokine production.
J. Immunol. 166: 4994-9, 2001.
[Journal]
18)  Martínez A, Hodge DL, Garayoa M, Young HA, Cuttitta F.
Alternative splicing of the proadrenomedullin gene results in differential expression of gene products.
J. Mol. Endocrinol. 27: 31-41, 2001.
[Journal]
19)  Hodge DL, Charron T, Stabile LP, Klautky SA, Salati LM.
Structural characterization and tissue-specific expression of the mouse glucose-6-phosphate dehydrogenase gene.
DNA Cell Biol. 17: 283-91, 1998.
[Journal]
20)  Hodge DL, Salati LM.
Nutritional regulation of the glucose-6-phosphate dehydrogenase gene is mediated by a nuclear posttranscriptional mechanism.
Arch. Biochem. Biophys. 348: 303-12, 1997.
[Journal]
21)  Stabile LP, Hodge DL, Klautky SA, Salati LM.
Posttranscriptional regulation of glucose-6-phosphate dehydrogenase by dietary polyunsaturated fat.
Arch. Biochem. Biophys. 332: 269-79, 1996.
[Journal]
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This page was last updated on 4/9/2014.