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Our Science – Yang Website

De Yang, M.D., Ph.D.

Selected Publications

1)  Yang D, Wei F, Tewary P, Howard OM, Oppenheim JJ.
Alarmin-induced cell migration.
Eur. J. Immunol. 43: 1412-8, 2013.
2)  Tewary P, de la Rosa G, Sharma N, Rodriguez LG, Tarasov SG, Howard OM, Shirota H, Steinhagen F, Klinman DM, Yang D, Oppenheim JJ.
ß-Defensin 2 and 3 promote the uptake of self or CpG DNA, enhance IFN-a production by human plasmacytoid dendritic cells, and promote inflammation.
J. Immunol. 191: 865-74, 2013.
3)  Yang D, Postnikov YV, Li Y, Tewary P, de la Rosa G, Wei F, Klinman D, Gioannini T, Weiss JP, Furusawa T, Bustin M, Oppenheim JJ.
High-mobility group nucleosome-binding protein 1 acts as an alarmin and is critical for lipopolysaccharide-induced immune responses.
J. Exp. Med. 209: 157-71, 2012.
4)  Yang D, Zhao Y, Guo H, Li Y, Tewary P, Xing G, Hou W, Oppenheim JJ, Zhang N.
[Gd@C(82)(OH)(22)](n) nanoparticles induce dendritic cell maturation and activate Th1 immune responses.
ACS Nano. 4: 1178-86, 2010.
5)  Tewary P, Yang D, de la Rosa G, Li Y, Finn MW, Krensky AM, Clayberger C, Oppenheim JJ.
Granulysin activates antigen-presenting cells through TLR4 and acts as an immune alarmin.
Blood. 116: 3465-74, 2010.
6)  Röhrl J, Yang D, Oppenheim JJ, Hehlgans T.
Human beta-defensin 2 and 3 and their mouse orthologs induce chemotaxis through interaction with CCR2.
J. Immunol. 184: 6688-94, 2010.
7)  Röhrl J, Yang D, Oppenheim JJ, Hehlgans T.
Specific binding and chemotactic activity of mBD4 and its functional orthologue hBD2 to CCR6-expressing cells.
J. Biol. Chem. 285: 7028-34, 2010.
8)  Yang D, Oppenheim JJ.
Alarmins and antimicrobial immunity.
Med. Mycol. 47 Suppl 1: S146-53, 2009.
9)  Yang D, de la Rosa G, Tewary P, Oppenheim JJ.
Alarmins link neutrophils and dendritic cells.
Trends Immunol. 30: 531-7, 2009.
10)  Yang D, Tewary P, de la Rosa G, Wei F, Oppenheim JJ.
The alarmin functions of high-mobility group proteins.
Biochim. Biophys. Acta. 1799: 157-63, 2009.
Click Here to View Expanded Bibliography.

This page was last updated on 4/16/2014.