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Our Science – Chen Website

Xin Chen, M.D., Ph.D.

Selected Publications

1)  Chen X, Yang Y, Zhou Q, Weiss JM, Howard OZ, McPherson JM, Wakefield LM, Oppenheim JJ.
Effective Chemoimmunotherapy with Anti-TGFß Antibody and Cyclophosphamide in a Mouse Model of Breast Cancer.
PLoS ONE. 9: e85398, 2014.
2)  Zhou Q, Hu Y, Howard OM, Oppenheim JJ, Chen X.
In vitro generated Th17 cells support the expansion and phenotypic stability of CD4(+)Foxp3(+) regulatory T cells in vivo.
Cytokine. 65: 56-64, 2014.
3)  Hu Y, Xiao H, Shi T, Oppenheim JJ, Chen X.
Progranulin promotes TNF-induced proliferation of suppressive mouse CD4(+) Foxp3(+) regulatory T cells.
Immunology. 2014.
4)  Weiss JM, Subleski JJ, Back T, Chen X, Watkins SK, Yagita H, Sayers TJ, Murphy WJ, Wiltrout RH.
Regulatory T Cells and Myeloid-Derived Suppressor Cells in the Tumor Microenvironment Undergo Fas-Dependent Cell Death during IL-2/aCD40 Therapy.
J. Immunol. 2014.
5)  Chen X, Oppenheim JJ.
Th17 cells and Tregs: unlikely allies.
J. Leukoc. Biol. 2014.
6)  Chen X, Wu X, Zhou Q, Howard OM, Netea MG, Oppenheim JJ.
TNFR2 is critical for the stabilization of the CD4+Foxp3+ regulatory T. cell phenotype in the inflammatory environment.
J. Immunol. 190: 1076-84, 2013.
7)  Griessl S, Chen X, Oppenheim J, Maennel D.
THE DUAL ROLE OF TNF ON T CELL ACTIVATION. In: Advances in Experimental Medicine and Biology. Volume 691:692-693.
Berlin: SPRINGER-VERLAG BERLIN; 2011. [Book]
8)  Chen X, Oppenheim JJ.
Comment on "Interplay between TNF and Regulatory T Cells in a TNF-Driven Murine Model of Arthritis".
J. Immunol. 187: 1527, 2011.
9)  Chen X, Oppenheim JJ.
Contrasting effects of TNF and anti-TNF on the activation of effector T cells and regulatory T cells in autoimmunity.
FEBS Lett. 585: 3611-8, 2011.
10)  Chertov O, Zhang N, Chen X, Oppenheim JJ, Lubkowski J, McGrath C, Sowder RC, Crise BJ, Malyguine A, Kutzler MA, Steele AD, Henderson EE, Rogers TJ.
Novel Peptides Based on HIV-1 gp120 Sequence with Homology to Chemokines Inhibit HIV Infection in Cell Culture.
PLoS ONE. 6: e14474, 2011.
Click Here to View Expanded Bibliography.

This page was last updated on 5/16/2014.