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Our Science – Barr Website

Valarie A. Barr, Ph.D.

Selected Publications

1)  Coussens NP, Hayashi R, Brown PH, Balagopalan L, Balbo A, Akpan I, Houtman JC, Barr VA, Schuck P, Appella E, Samelson LE.
Multipoint binding of the SLP-76 SH2 domain to ADAP is Critical for Oligomerization of SLP-76 Signaling Complexes in Stimulated T cells.
Mol. Cell. Biol. 2013.
[Journal]
2)  Balagopalan L, Barr VA, Kortum RL, Park AK, Samelson LE.
Cutting edge: cell surface linker for activation of T cells is recruited to microclusters and is active in signaling.
J. Immunol. 190: 3849-53, 2013.
[Journal]
3)  Sherman E, Barr VA, Samelson LE.
Resolving multi-molecular protein interactions by photoactivated localization microscopy.
Methods. 59: 261-9, 2013.
[Journal]
4)  Sherman E, Barr V, Samelson LE.
Super-resolution characterization of TCR-dependent signaling clusters.
Immunol. Rev. 251: 21-35, 2013.
[Journal]
5)  Clayberger C, Finn MW, Wang T, Saini R, Wilson C, Barr VA, Sabatino M, Castiello L, Stroncek D, Krensky AM.
15 kDa Granulysin Causes Differentiation of Monocytes to Dendritic Cells but Lacks Cytotoxic Activity.
J Immunol. 188: 6119-26, 2012.
[Journal]
6)  Luo R, Akpan IO, Hayashi R, Sramko M, Barr V, Shiba Y, Randazzo PA.
GTP-binding Protein-like Domain of AGAP1 Is Protein Binding Site That Allosterically Regulates ArfGAP Protein Catalytic Activity.
J. Biol. Chem. 287: 17176-85, 2012.
[Journal]
7)  Lesourne R, Zvezdova E, Song K, El-Khoury D, Uehara S, Barr VA, Samelson LE, Love PE.
Interchangeability of themis1 and themis2 in thymocyte development reveals two related proteins with conserved molecular function.
J. Immunol. 189: 1154-61, 2012.
[Journal]
8)  Balagopalan L, Ashwell BA, Bernot KM, Akpan IO, Quasba N, Barr VA, Samelson LE.
Enhanced T-cell signaling in cells bearing linker for activation of T-cell (LAT) molecules resistant to ubiquitylation.
Proc. Natl. Acad. Sci. U.S.A. 108: 2885-90, 2011.
[Journal]
9)  Sherman E, Barr V, Manley S, Patterson G, Balagopalan L, Akpan I, Regan CK, Merrill RK, Sommers CL, Lippincott-Schwartz J, Samelson LE.
Functional nanoscale organization of signaling molecules downstream of the T cell antigen receptor.
Immunity. 35: 705-20, 2011.
[Journal]
10)  Balagopalan L, Sherman E, Barr VA, Samelson LE.
Imaging techniques for assaying lymphocyte activation in action.
Nat. Rev. Immunol. 11: 21-33, 2011.
[Journal]
Click Here to View Expanded Bibliography.

This page was last updated on 9/16/2013.