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Our Science – Ambs Website

Stefan Ambs, Ph.D., M.P.H.

Selected Publications

1)  Terunuma A, Putluri N, Mishra P, Mathé EA, Dorsey TH, Yi M, Wallace TA, Issaq HJ, Zhou M, Killian JK, Stevenson HS, Karoly ED, Chan K, Samanta S, Prieto D, Hsu TY, Kurley SJ, Putluri V, Sonavane R, Edelman DC, Wulff J, Starks AM, Yang Y, Kittles RA, Yfantis HG, Lee DH, Ioffe OB, Schiff R, Stephens RM, Meltzer PS, Veenstra TD, Westbrook TF, Sreekumar A, Ambs S.
MYC-driven accumulation of 2-hydroxyglutarate is associated with breast cancer prognosis.
J. Clin. Invest. 124: 398-412, 2014.
[Journal]
2)  Hudson RS, Yi M, Esposito D, Watkins SK, Hurwitz AA, Yfantis HG, Lee DH, Borin JF, Naslund MJ, Alexander RB, Dorsey TH, Stephens RM, Croce CM, Ambs S.
MicroRNA-1 is a candidate tumor suppressor and prognostic marker in human prostate cancer.
Nucleic Acids Res. 40: 3689-3703, 2012.
[Journal]
3)  Glynn SA, Boersma BJ, Dorsey TH, Yi M, Yfantis HG, Ridnour LA, Martin DN, Switzer CH, Hudson RS, Wink DA, Lee DH, Stephens RM, Ambs S.
Increased NOS2 predicts poor survival in estrogen receptor-negative breast cancer patients.
J. Clin. Invest. 120: 3843-54, 2010.
[Journal]
4)  Wallace TA, Prueitt RL, Yi M, Howe TM, Gillespie JW, Yfantis HG, Stephens RM, Caporaso NE, Loffredo CA, Ambs S.
Tumor immunobiological differences in prostate cancer between African-American and European-American men.
Cancer Res. 68: 927-36, 2008.
[Journal]
5)  Ambs S, Merriam WG, Ogunfusika MO, Bennett WP, Ishibe N, Hussain SP, Tzeng EE, Geller DA, Billiar TR, Harris CC.
p53 and vascular endothelial growth factor regulate tumor growth of NOS2-expressing human carcinoma cells.
Nat Med. 4: 1371-6, 1998.
[Journal]
6)  Subramanian M, Francis P, Bilke S, Li XL, Hara T, Lu X, Jones MF, Walker RL, Zhu Y, Pineda M, Lee C, Varanasi L, Yang Y, Martinez LA, Luo J, Ambs S, Sharma S, Wakefield LM, Meltzer PS, Lal A.
A mutant p53/let-7i-axis-regulated gene network drives cell migration, invasion and metastasis.
Oncogene. [Epub ahead of print], 2014.
[Journal]
7)  Wallace TA, Downey RF, Seufert CJ, Schetter A, Dorsey TM, Johnson CA, Goldman R, Loffredo CA, Yan P, Sullivan FJ, Giles FJ, Wang-Johanning F, Ambs S, Glynn SA.
Elevated HERV-K mRNA expression in PBMC is associated with a prostate cancer diagnosis particularly in older men and smokers.
Carcinogenesis. 2014.
[Journal]
8)  Downey RF, Sullivan FJ, Wang-Johanning F, Ambs S, Giles FJ, Glynn SA.
Human endogenous retrovirus K and cancer: Innocent bystander or tumorigenic accomplice?.
Int. J. Cancer. 2014.
[Journal]
9)  Wang-Johanning F, Li M, Esteva FJ, Hess KR, Yin B, Rycaj K, Plummer JB, Garza JG, Ambs S, Johanning GL.
Human endogenous retrovirus type K antibodies and mRNA as serum biomarkers of early-stage breast cancer.
Int. J. Cancer. 134: 587-95, 2014.
[Journal]
10)  Heinecke JL, Ridnour LA, Cheng RY, Switzer CH, Lizardo MM, Khanna C, Glynn SA, Hussain SP, Young HA, Ambs S, Wink DA.
Tumor microenvironment-based feed-forward regulation of NOS2 in breast cancer progression.
Proc. Natl. Acad. Sci. U.S.A. [Epub ahead of print], 2014.
[Journal]
Click Here to View Expanded Bibliography.

This page was last updated on 6/16/2014.