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Our Science – McMahon Website

James B. McMahon, Ph.D.

Selected Publications

1)  Beutler J.
Koehn F, eds.
Natural Products as Tools for Discovering New Cancer Targets. In: Natural Products and Cancer Drug Discovery.
New York: Humana Press; 2013. p. 213-237 [Book Chapter]
2)  Kanduluru AK, Banerjee P, Beutler JA, Fuchs PL.
A Convergent Total Synthesis of the Potent Cephalostatin/Ritterazine Hybrid -25-epi Ritterostatin GN1N.
J. Org. Chem. 2013.
[Journal]
3)  Takebe Y, Saucedo CJ, Lund G, Uenishi R, Hase S, Tsuchiura T, Kneteman N, Ramessar K, Tyrrell DL, Shirakura M, Wakita T, McMahon JB, O'Keefe BR.
Antiviral lectins from red and blue-green algae show potent in vitro and in vivo activity against hepatitis C virus.
PLoS ONE. 8: e64449, 2013.
[Journal]
4)  Dossou KS, Devkota KP, Kavanagh PV, Beutler JA, Egan JM, Moaddel R.
Development and preliminary validation of a plate-based CB1/CB2 receptor functional assay.
Anal. Biochem. 437: 138-43, 2013.
[Journal]
5)  Winter DK, Endoma-Arias MA, Hudlicky T, Beutler JA, Porco JA.
Enantioselective total synthesis and biological evaluation of (+)-kibdelone a and a tetrahydroxanthone analogue.
J. Org. Chem. 78: 7617-26, 2013.
[Journal]
6)  Sourbier C, Scroggins BT, Ratnayake R, Prince TL, Lee S, Lee MJ, Nagy PL, Lee YH, Trepel JB, Beutler JA, Linehan WM, Neckers L.
Englerin A stimulates PKC? to inhibit insulin signaling and to simultaneously activate HSF1: pharmacologically induced synthetic lethality.
Cancer Cell. 23: 228-37, 2013.
[Journal]
7)  Masaoka T, Chung S, Caboni P, Rausch JW, Wilson JA, Taskent-Sezgin H, Beutler JA, Tocco G, Le Grice SF.
Exploiting Drug-Resistant Enzymes as Tools To Identify Thienopyrimidinone Inhibitors of Human Immunodeficiency Virus Reverse Transcriptase-Associated Ribonuclease H.
J. Med. Chem. 2013.
[Journal]
8)  Henrich CJ, Budhu A, Yu Z, Evans JR, Goncharova EI, Ransom TT, Wang XW, McMahon JB.
High-throughput Screening for Identification of Inhibitors of EpCAM-Dependent Growth of Hepatocellular Carcinoma Cells.
Chem Biol Drug Des. 82: 131-9, 2013.
[Journal]
9)  Henrich CJ, Beutler JA.
Matching the power of high throughput screening to the chemical diversity of natural products.
Nat Prod Rep. 2013.
[Journal]
10)  Beutler J, Cragg G, Newman D.
Chibale K, Davies-Coleman M, Masimirembwa C, eds.
The National Cancer Institute and Natural Product Based Drug Discovery in Africa. In: Drug Discovery in Africa.
New York: Springer; 2012. p. 29-51 [Book Chapter]
Click Here to View Expanded Bibliography.

This page was last updated on 9/4/2013.