Our Science – Kuehn Website
Michael R. Kuehn, Ph.D.
Selected Publications |
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| 1)
Liu J, Li Q, Kuehn MR, Litingtung Y, Vokes SA, Chiang C. Sonic hedgehog signaling directly targets Hyaluronic Acid Synthase 2, an essential regulator of phalangeal joint patterning. Dev. Biol. 375: 160-71, 2013. [Journal] |
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| 2)
Lezin G, Kosaka Y, Yost HJ, Kuehn MR, Brunelli L. A one-step miniprep for the isolation of plasmid DNA and lambda phage particles. PLoS ONE. 6: e23457, 2011. [Journal] |
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| 3)
Lezin G, Kuehn MR, Brunelli L. Hofmeister series salts enhance purification of plasmid DNA by non-ionic detergents. Biotechnol. Bioeng. 108: 1872-82, 2011. [Journal] |
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| 4)
Tripathi P, Guo Q, Wang Y, Coussens M, Liapis H, Jain S, Kuehn MR, Capecchi MR, Chen F. Midline signaling regulates kidney positioning but not nephrogenesis through Shh. Dev. Biol. 340: 518-27, 2010. [Journal] |
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| 5)
Akagi K, Stephens RM, Li J, Evdokimov E, Kuehn MR, Volfovsky N, Symer DE. MouseIndelDB: a database integrating genomic indel polymorphisms that distinguish mouse strains. Nucleic Acids Res. 38: D600-6, 2010. [Journal] |
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| 6)
Sharma P, Murillas R, Zhang H, Kuehn MR. N4BP1 is a newly identified nucleolar protein that undergoes SUMO-regulated polyubiquitylation and proteasomal turnover at promyelocytic leukemia nuclear bodies. J. Cell. Sci. 123: 1227-34, 2010. [Journal] |
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| 7)
Dahle O, Kumar A, Kuehn MR. Nodal signaling recruits the histone demethylase jmjd3 to counteract polycomb-mediated repression at target genes. Sci Signal. 3: ra48, 2010. [Journal] |
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| 8)
Shirakawa H, Rochman M, Furusawa T, Kuehn MR, Horigome S, Haketa K, Sugita Y, Inada T, Komai M, Bustin M. The nucleosomal binding protein NSBP1 is highly expressed in the placenta and modulates the expression of differentiation markers in placental Rcho-1 cells. J. Cell. Biochem. 106: 651-8, 2009. [Journal] |
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| 9)
Kumar A, Lualdi M, Lewandoski M, Kuehn MR. Broad mesodermal and endodermal deletion of Nodal at postgastrulation stages results solely in left/right axial defects. Dev. Dyn. 237: 3591-601, 2008. Full Text Article. [Journal] |
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| 10)
Evdokimov E, Sharma P, Lockett SJ, Lualdi M, Kuehn MR. Loss of SUMO1 in mice affects RanGAP1 localization and formation of PML nuclear bodies, but is not lethal as it can be compensated by SUMO2 or SUMO3. J. Cell. Sci. 121: 4106-13, 2008. [Journal] |
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| 11)
Oberst A, Malatesta M, Aqeilan RI, Rossi M, Salomoni P, Murillas R, Sharma P, Kuehn MR, Oren M, Croce CM, Bernassola F, Melino G. The Nedd4-binding partner 1 (N4BP1) protein is an inhibitor of the E3 ligase Itch. Proc. Natl. Acad. Sci. U.S.A. 104: 11280-5, 2007. [Journal] |
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| 12)
Kumar A, Yamaguchi T, Sharma P, Kuehn MR. Transgenic mouse lines expressing Cre recombinase specifically in posterior notochord and notochord. Genesis. 45: 729-36, 2007. [Journal] |
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| 13)
Kuehn MR. Mouse Ubc9 knockout: many path(way)s to ruin. Dev Cell. 9: 727-8, 2005. [Journal] |
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| 14)
Yamaguchi T, Sharma P, Athanasiou M, Kumar A, Yamada S, Kuehn MR. Mutation of SENP1/SuPr-2 reveals an essential role for desumoylation in mouse development. Mol Cell Biol. 25: 5171-82, 2005. [Journal] |
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| 15)
Murillas R, Simms KS, Hatakeyama S, Weissman AM, Kuehn MR. Identification of developmentally expressed proteins that functionally interact with Nedd4 ubiquitin ligase. J Biol Chem. 277: 2897-2907, 2002. [Journal] |
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| 16)
Lowe LA, Yamada S, Kuehn MR. Genetic dissection of nodal function in patterning the mouse embryo. Development. 128: 1831-1843, 2001. [Journal] |
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| 17)
Kumar A, Novoselov V, Celeste AJ, Wolfman NM, ten Dijke P, Kuehn MR. Nodal signaling uses activin and transforming growth factor-beta receptor-regulated Smads. J Biol Chem. 276: 656-661, 2001. [Journal] |
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| 18)
Izraeli S, Lowe LA, Bertness VL, Good DJ, Dorward DW, Kirsch IR, Kuehn MR. The SIL gene is required for mouse embryonic axial development and left-right specification. Nature. 399: 691-694, 1999. [Journal] |
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| 19)
Lowe LA, Supp DM, Sampath K, Yokoyama T, Wright CV, Potter SS, Overbeek P, Kuehn MR. Conserved left-right asymmetry of nodal expression and alterations in murine situs inversus. Nature. 381: 158-61, 1996. [Journal] |
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| 20)
Levin M, Johnson RL, Stern CD, Kuehn M, Tabin C. A molecular pathway determining left-right asymmetry in chick embryogenesis. Cell. 82: 803-14, 1995. [Journal] |
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| 21)
Zhou X, Sasaki H, Lowe L, Hogan BL, Kuehn MR. Nodal is a novel TGF-beta-like gene expressed in the mouse node during gastrulation. Nature. 361: 543-7, 1993. [Journal] |
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This page was last updated on 4/16/2013.
